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Vasoactive Intestinal Peptide Tumor

Vasoactive Intestinal Peptide Tumor – General Information

Vasoactive Intestinal Peptide Tumor, also known as VIPoma is a rare cancer consisting in tumor cells that can appear from certain cells that produce hormones called islet cells. These types of cells are generally located in the patient’s pancreas, which is an organ that produces a hormone called insulin and other substances that help the digestion. The islet cells can also be located in or around the patient’s adrenal glands that secret hormones and are located above each kidney. There are cases in which the tumors continue to produce high quantities of hormones, especially the one known as vasoactive intestinal peptide. This hormone has an important role in water transportation in the patient’s intestines. That is why the main symptom of the disease is watery diarrhea, because of the excessive amount of this hormone produced by the glands. Due to the fact that the tumor is developing from the islet cells, the condition is referred to as a type of islet cells tumor. When the first signs and symptoms appear, Vasoactive Intestinal Peptide Tumor is also known as Verner-Morrison syndrome, which comes from the two doctors that first discovered and described this medical condition. There are cases in which, if is not treated properly or not treated at the right moment, Vasoactive Intestinal Peptide Tumor can metastasize, spreading to the other organs. It is very important to contact the doctor as soon as possible if the patient’s experiences one of the specific signs and symptoms caused by this kind of medical condition.

Vasoactive Intestinal Peptide Tumor – Symptoms

In most cases, Vasoactive Intestinal Peptide Tumor causes no signs and symptoms in the early stages. Once the medical condition progressed to a more severe stage, and the tumor produced a big number of hormones, especially vasoactive intestinal peptide, the patient starts to experience certain signs and symptoms which can include watery diarrhea, dehydration, leg cramps or muscle weakness, which are usually cause by the reduced amounts of potassium in the patient’s blood, that take place due to diarrhea, flushing, reddening or swelling of the skin of the face and neck, abdominal pain and cramping and bowel obstruction. There are also cases when, in treating Vasoactive Intestinal Peptide Tumor, the medicines administrated can cause certain side effects that can be experienced by the patient as slow or irregular heartbeats, gallbladder problems, stomach pain, pancreatitis, which is characterized as a pain in the upper stomach or back, nausea, vomiting, fever, bloating, yellowing of the skin or eyes, thyroid problems, which can be detected by blood tests, low blood sugar, which can cause headache, confusion, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, nausea or high blood sugar, which can cause increased thirst and urination, flushed or dry skin and drowsiness.

Vasoactive Intestinal Peptide Tumor – Treatment

The first stage in treating Vasoactive Intestinal Peptide Tumor is the prompt replacement of fluid and electrolyte losses. In most cases, the specific signs and symptoms of the electrolyte loss can include cardiac arrhythmias, neuromuscular deficits, profound shock, and cardiovascular collapse. The fluid that is used to replace these losses is usually an isotonic electrolyte solution that contains adequate doses of potassium, sodium and base. If the patient has been diagnosed with the tumor, the first treatment option is complete surgical removal. If the tumor can not be removed completely, the second treatment option is a procedure called surgical debulking, which can provide a palliative effect. In treating Vasoactive Intestinal Peptide Tumor the most common medicine used is Sandostatin. This type of drug is an artificial protein that is considered similar to a hormone in the patient’s body called somatostatin. The medicine acts by lowering the concentration of certain substances in the patient’s body, which can include insulin and glucagons, both involved in regulating the patient’s blood sugar levels, growth hormone, and certain chemicals involved in digestion. This medicine is also used to treat acromegaly and to reduce flushing episodes and watery diarrhea triggered by malignant tumors, carcinoid syndromes or tumors called Vasoactive Intestinal Peptide Tumors.

There are cases in which the doctor can use the medicine in other purposes than those listed in the medication guide. Before administrating the Sandostatin medicine the doctor should know if the patient suffers from diabetes, gallbladder disorders, kidney disease or a thyroid dysfunction. One of the contraindications for this medicine is that it should not be administrated in combination with cyclosporine, a medicine that can be prescribed as Neoral, Sandimmune or Gengraf.

To treat Vasoactive Intestinal Peptide Tumor, Sandostatin is administrated using an injection under the patient’s skin or blood vessel. It is very important not to inject yourself the medicine if you are patient not fully aware of how to apply it. There are cases in which the medicine has not been administered properly and thus, the patient may experience certain side effects that can include severe stomach pain, fever, bloating, vomiting, nausea, and jaundice, characterized by yellowing of the patient’s skin or eye. There are some tests with the help of which the doctor can know if the medicine is dealing with Vasoactive Intestinal Peptide Tumor and can order some tests of the patient’s blood or urine. To reduce the discomfort caused by the medicine administration, you can put it in the refrigerator and keep it there for about 30 minutes, but without allowing the medicine to freeze. It is very important to let the medicine reach the room temperature before administrating it, but it is also important to never warm the medicine in hot water or a microwave. There are cases in which the patient’s organism did not respond to the medicine and he can experience certain symptoms such as slow or irregular heartbeats, stomach pain, pancreatitis, thyroid problems, low blood sugar or high blood sugar, which can lead to the worsening of the condition, eventually causing death.




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