Buy Amyotrophic Lateral Sclerosis Medications Online
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Amyotrophic Lateral SclerosisAmyotrophic Lateral Sclerosis – General InformationAmyotrophic Lateral Sclerosis or ALS is a disorder that is also known as Lou Gehrig's disease and Maladie de Charcot. This disease is considered to be a progressive disorder, in most cases a fatal one. It is known to be a neurodegenerative disease that is provoked by the degeneration of motor neurons, which are the nerve cells in the central nervous system (CNS), and have the role in controlling voluntary muscle movement. It is one of the many motor neuron diseases in which the disorder causes symptoms such as muscle weakness and atrophy of the whole body, in which the both upper and lower motor neurons degenerate and die, thus making sending messages to muscles impossible. Unable to perform, the muscles progressively weaken, atrophy, and develop fasciculations, or twitches, due to the denervation. The patient can, in the last phase, lose his ability to initiate or control any voluntary movement except eye movement. The patient’s cognitive function is in most cases preserved, except in some rare situations when Amyotrophic Lateral Sclerosis can be associated with frontotemporal dementia. However, many studies have many reports of more subtle cognitive changes in many patients suffering of this type of medical condition. The disorder is one of the most encountered neuromuscular conditions in all over the world, and patients of all races and ethnic backgrounds can be affected. About one or two patients in 100.000 can develop the disorder every year. Amyotrophic Lateral Sclerosis usually affects patients with the age between forty and sixty years, but younger and older patients may also have the disease. Generally, men are affected more often than women.Amyotrophic Lateral Sclerosis – SymptomsThe onset of the Amyotrophic Lateral Sclerosis disease can be so subtle that the symptoms are usually ignored. The first and the most subtle symptoms can appear such as twitching, cramping, or stiffness of muscles. The muscle weakness can affect an arm or a leg and slurred or nasal speech. These common symptoms then develop into more obvious weakness or atrophy that can lead to a physician to diagnose the motor neuron disease. Regardless of the area on the body early affected by the disease, the main symptom such as muscle weakness and atrophy usually spread to other areas of the body as the disease evolves. Patients usually first feel the increasing difficulty moving, swallowing called dysphagia, and speaking or forming words (called dysarthria). Symptoms in which the upper motor neuron is involved include tight and stiff muscles, called spasticity or exaggerated reflexes, called hyperreflexia, or the appearance of an overactive gag reflex. The uncommon reflex generally called Babinski's sign (when the large toe extends upward as the sole of the foot is stimulated) is also a sign that indicates the upper motor neuron involvement. The sign and symptoms of lower motor neuron involvement include muscle weakness and atrophy, muscle cramps, and fleeting twitches of muscles that may be sensed under the skin, like fasciculations. Less than half of the patients have pseudobulbar symptoms, also called emotional lability, which is characterized by uncontrollable laughter, crying or smiling. Patients who suffer from Amyotrophic Lateral Sclerosis should seek medical attention when he encounters one of the symptoms above.Amyotrophic Lateral Sclerosis – TreatmentThere is no official cure for Amyotrophic Lateral Sclerosis. But experts have developed the first drug treatment for this condition called Riluzole or Rilutek. Riluzole has the effect of reducing the damage to motor neurons by decreasing the production of glutamate. Medical trials for patients suffering of this type of disease proved that Riluzole prolongs survival by several months, and can have a higher survival benefit for those with a bulbar onset. The medicine has also the effect of extending the period before the patient needs ventilation support. However, a treatment with Riluzole can not reverse the damage that has already been done to the patient’s motor neurons, and patients using this medicine for a prolonged period of time have to be monitored for liver damage and other possible / potential side effects. This is the first specific treatment that offers hope that the progression of Amyotrophic Lateral Sclerosis could one day be reversed by new drugs and combinations between them. Other treatments available to cure this kind of disease are prescribed to relieve the symptoms and improve the way of life for the individuals. These medical trials are best supported by medical teams of health care professionals including physicians, pharmacists, physical or occupational and speech therapists, nutritionists, social workers or home care nurses. Treating patients who suffer from Amyotrophic Lateral Sclerosis, these teams can prescribe a specific plan of medical and physical therapy then get special equipment which has the goal of keeping patients as mobile and healthy as possible. Usually, doctors prescribe medications which have the effect of reducing symptoms such as fatigue, ease muscle cramps, control spasticity, and reducing excess saliva and phlegm. There are many types of drugs that help patients in relieving some other symptoms such as pain, depression, sleep disturbances, and constipation. Pharmacists can intervene with advice on the best prescription of medications or can easily monitor a patient's prescriptions to reduce the risks of drug interactions. Patients can also consider another type of treatment which consists in a process that includes a machine that inflates and deflates the lungs. To have any effect, this can require a tube that gets all the way from the nose or mouth to the windpipe, or trachea, and for a long term effect, a process such as a tracheotomy, which consists in a plastic breathing tube which is inserted directly in the patient's trachea through an access point in the neck. Patients and their relatives can take in consideration many factors when deciding how and when to use one of these treatment methods. The ventilation device differs in his effect on the patient's way of life and in his economy. The ventilation support process can relieve affections in breathing and can prolong the survival and it doesn’t affect the progression of the Amyotrophic Lateral Sclerosis. Usually, patients want to be fully informed about these treatment options and the long term effects in the way of life without much movement before they can make any decision about the ventilation support. It must be known that many patients using long term tracheostomy intermittent positive pressure ventilation with deflated cuffs or cuffless tracheostomy tubes are now able to speak. This process preserves the speech in many patients with long term mechanical ventilation. |
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