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Behcets DiseaseBehcet’s Disease – General InformationBehcet’s Disease or beh-CETS is also known as Behcet's syndrome and is considered a rare condition which can cause severe inflammation in blood vessels in the whole body. The inflammation of this type of disease can progress to big a variety of signs and symptoms that can appear unrelated. Behcet’s Disease in most of the cases affects men and women over 20 years but younger than 30 years, but cases in which children and older adults also developed the condition have rarely appeared. This type of disease is the most encountered disorder in countries in the Middle East and Asia, such as Turkey, Iran, Japan and China. Because this kind of disease appears in both men and women, the disease is considered to be more severe in men. The disease is also usually more chronic when it appears at an earlier age. There is no cure available for this disease and the signs and symptoms of the disease which are characterized by mouth sores, skin rashes and lesions, or genital sores and can vary from patient to patient and usually appear and progress on their own. The treatments goal is to reduce the signs and symptoms of this kind of disease and try to prevent any major complications, such as blindness. Behcet’s Disease is usually caused by a series of genetic and environmental factors. Some studies shown that a virus or bacterium can cause the disease in patients who suffer with certain genetic features. There are also other causes that could set off the immune system and can include the chemicals and heavy metals.Behcet’s Disease – SymptomsThe signs and the symptoms of Behcet’s Disease usually differ from patient to patient. These signs and symptoms that the patient can encounter depend on what areas of the body have been affected by the inflammation of this kind of disease. The body parts that are most usually affected by the disease include the mouth, where it can develop painful sores, just like the cancer sores and are the most encountered symptoms of this kind of disease. The sores start as raised, round lesions on the lips, gums, cheeks and tongue areas. The sore symptoms progress two to five days, when they become shallow ulcers and present a white or yellow covering. These affections usually heal in more than seven days, but the recurrence appears fast. Many mouth affections can appear at the same time, and the sores can be more persistent in chronic cases. Skin affection can also appear in patients suffering with Behcet’s Disease and these skin lesions usually vary. Some patients can have acne-like sores all over their bodies. Some patients can have red, raised and tender lumps on the surface of the skin. Usually, skin affection can clear up on their own in more than ten days, but in the most of the cases usually recur. Patients suffering with Behcet’s Disease can also develop sores on the genitals. These affections most commonly appear on the penis or on the vulva. The sores occur like round, red and ulcerated lesions. The genital affections are in most of the cases painful and usually lead to some scars.Behcet’s Disease – TreatmentThere is no cure available for Behcet’s Disease and if your signs and symptoms of this type of disease are moderate, the doctor can prescribe medications to control mild flares in pain and inflammation. The patient is not obliged to take the treatment between flares. But if any signs or symptoms are in a chronic stage, the doctor can prescribe systemic medications to monitor the signs or symptoms of this disease in the whole your body, in combination with the medications for the temporary flares. The treatment used to treat Behcet’s Disease includes a treatment for individual signs and symptoms. This type of disease can develop and progress on its own in fits of flares and remissions. The doctor’s job is to control the signs and symptoms the patient can experience during flares with drugs including skin creams, gels and ointments, which are considered topical medicines and are applied above the skin and genital sores having the effect of reducing the inflammation and relieving the pain. These types of medicines normally contain a corticosteroid medication which has the effect of reducing inflammation and an anesthetic to relieve the pain, mouth rinses, which are considered some special mouthwashes which have in their composition corticosteroids to relieve the pain of mouth sores and can reduce the discomfort, eyedrops (medicines that contain corticosteroids or other anti-inflammatory drugs and have the effect of relieving the pain and the redness in the eyes if the inflammation is mild). The chronic cases of Behcet’s Disease may need treatments to control the complications from the disease between flares. If the patient suffers with a moderate to severe stage of the disease, the doctor can prescribe corticosteroids, to control the inflammation, drugs that suppress the immune system, and also drugs that regulates the immune system.The corticosteroids which are prescribed as prednisone are used in combination with other drugs to reduce the inflammation provoked by the disease. Any signs and symptoms of this type of disease have a recurrence character when the corticosteroids are used alone, when the doctors usually prescribe them in combination with other medication to suppress the activity of your immune system, which are called immunosuppressive. The side effects of these corticosteroids can appear and can consist in stomach ulcers, high blood pressure and bone thinning, leading to osteoporosis. The immunosuppressive medicines are used to suppress your immune system, which has a good improvement in Behcet’s Disease. When these medicines suppress the immune system from protecting normal, healthy parts of the body, the immunosuppressive drugs have the effect of reducing the inflammation that the immune system can cause. The immunosuppressive medicines can play an important role in monitoring Behcet’s Disease, and are usually prescribed as azathioprine, or Imuran and Azasan, cyclosporine, or Sandimmune and cyclophosphamide, as Cytoxan. Because these drugs halt the action of the body’s immune system, they can cause a high risk of infection. There can also appear any side effects characterized as liver and kidney dysfunctions, low blood cell level or high blood pressure. |
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