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Beriberi

Beriberi General Information

If a person’s body has deficiency of vitamin B1 (thiamine) he suffers of Beriberi, a nervous system ailment. The alternative names of this disorder are: vitamin B1 deficiency or thiamine deficiency. The real meaning of this disease’s name is a phrase: “I can not, I can not”, and has a Singhalese origin showing the crippling effect that this disease can have on the victims. Beriberi also can affect other systems of the body, for example, the heart, digestive tract, muscles, or nerves. It is seen in many parts of the world, but is more common in some places of Southeast Asia, where the food is mainly based on rice meals. The dysfunction also affects more people from the USA who suffer from chronic alcoholism. People of all ages can get the disease. For many years doctors thought that this disease is caused by something that is in the food. Around 1900 it has been discovered that rice can actually help prevent the illness thanks to something that it contains. Scientists discovered that adults present different types of Beriberi: a wet form that attacks the circulatory system and the heart and a dry form characteristic for the nervous system. A patient develops both these forms, but the symptoms do not change and some of them predominate during the disease. In some cases a third form can appear, called shoshin, although this cardiovascular type is less common. In these patients, the symptoms appear suddenly leading to an acute heart failure. It is considered to be a fatal disease.

Beriberi Symptoms

Thiamine is part of the B vitamins and is involved in building the tissues and in the energy metabolism. The coenzyme TPP (thiamine pyrophosphate) results from combining thiamine with phosphate and is very important because transforms glucose into fat that will be stored in the tissues or glucose into energy. This is mainly why, when the organism has not got enough thiamine, problems appear because the energy functions that are essential are disturbed. Some special situations (pregnancy, an over-active metabolism, breastfeeding or prolonged fever) could decrease the quantity of thiamine in the body and cause symptoms that are the same as for Beriberi. This disease affects the gastrointestinal tract causing serious constipation, loss of the appetite, a small quantity of hydrochloric acid in the stomach, or indigestion. Once the cardiovascular system is touched by the disease, a patient will complain of sweating and a fast heart beat resulting in a weakening of the muscles of the heart. Edema (swellings) usually appears on the legs as the smooth muscles of the vessels are affected and the veins and arteries are relaxed. The glucose helps the nervous system to function normally. When Beriberi is in its early stages, the main symptoms are: poor memory, irritability and tiredness. If it is not treated, it could attack the peripheral nerves and provoking weakening of the muscles and loss of sensations. The symptoms are more pronounced in the area of the legs: the feet are felt like burning, the toes feel numb, and the calf muscles cramp and the muscles of the legs become sore. The patient finds walking far more difficult.

Beriberi Treatment

Beriberi is a rare disease, but you must call your health care provider if you consider that your diet is inadequate or is not well balanced, but also if you or your children present any of the symptoms that have been listed here. Beriberi is a disorder that can be easily prevented by having a proper diet that contains enough vitamin B1 and all other elements that keep the illness away. People who drink too much alcohol should try to quit or at least to cut down their daily portion in order to enable their organism to properly store and absorb the vitamins, especially thiamine. Mothers who are nursing must be very careful to have a diet rich in all vitamins so that the infant will have the right quantity of thiamine. When seeing a specialist, he or she will do a physical examination to see if there are signs of congestive failure of the heart. This exam may reveal fluids in the lungs, a fast beat of the heart, swellings in both lower legs, and difficulties while breathing.

A neurological exam is needed in the last stage of the disorder because it may show drooping of the eyelids, decreased reflexes, and coordination difficulties, problems in a person’s walk or other more couple of changes. The level of thiamine in the blood is measured with the help of some blood tests. Urine tests are also very helpful to identify if vitamin B1 can pass through urine. The goal of any treatment for Beriberi is to replace the thiamine that a person’s organism is lacking with the help of supplements based on thiamine that can be administrated by mouth or through an injection given into the muscle (an intramuscular shot) or with a solution that goes intravenously (into the veins) given for a couple of days. If the health state of the patient is severe, the doses are high, but smaller dosage can be administrated after several days if the patient starts to recover. Some doctors give additional treatments with some other kinds of vitamins. After some days of therapy, the patient must be tested; usually blood is taken to see if the supplements determined a response from the patient’s organism. The recovery is dramatic and can occur within hours. The health of a patients suffering from Beriberi can transform within just an hour. The diet is very important during the treatment. Thiamine is contained in fresh foods, for example fresh green vegetables, milk, fresh meat, fruits, legumes and in unrefined cereals. If a patient suffers from heart failure, he or she may receive as additional treatment diuretics to help the fluid in excess to be eliminated. Physical therapies are extraordinary effects if a person develops peripheral neuropathy or some other more symptoms of dry Beriberi. When an infant has the disease, vitamin B1 is given both to the breast feeding mother and to the infant until normal and healthy levels are reached. Left untreated, this illness can cause the patient’s death. However, with the proper treatment, full recovery is assured. Although, when the acute heart failure appears, the prognosis is worrying.


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