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Cryptococcosis

Cryptococcosis General Information

The infection known as Cryptococcosis is caused by the fungus C. neoformans. This fungus is found all around the world. It can be located in soil that contains bird droppings or on unwashed raw fruits. You might be more familiar to the other names of this medical condition: European blastomycosis, cryptococcal meningitis, torulosis, Busse-Buschke disease, or torular meningitis. The disease was rare until a few years ago when the AIDS epidemic started. Very sensitive to Cryptococcosis are those people who follow a long-term therapy based on drugs that suppress the immune system, such as chemo drugs or corticosteroids, those who have sarcoidosis, Hodgkin’s disease or other lymphomas. For them, this fungal infection can be really life-threatening. In healthy individuals, this illness is less common. This disorder usually attacks the meninges (the tissues that cover the spinal cord and the brain), provoking meningitis (an inflammation of these membranes that is very fatal), the skin and the lungs, but some other organs may also be involved because this disease spreads very frequently. A person gets infected with the Cryptococcus neoformans by inhaling it. In the past 15 years the prevalence of this infection has been increasing for numerous reasons, and one of them is the increased incidence of patients who use immunosuppressive drugs and of patients who are suffering from AIDS. The infections caused by fungus in humans can be divided in three categories: cryptococcal meningitis, cutaneous or wound Cryptococcosis and cryptococcal pulmonary. Many studies showed that an infection of this kind is more dangerous for men than for women. The average age of sick patients is around 45 years old.

Cryptococcosis Symptoms

After the fungus enters the body and reaches the lungs, the immune system can heal the organism without any medical treatment. Thanks to the normal functioning of the immune system the person will not develop any symptoms or complications and he or she can not infect any healthy individuals. But these cases of asymptomatic patients are generally rare because in many cases the immune system is not very strong and it enables the disorder to remain in the lungs or to spread throughout the body. Specialists use to say about Cryptococcosis that is an opportunistic disease. More than 5% of the patients with AIDS get this fungal infection. In case the microorganism is not killed by the body, it will grow and form nodules in the lungs (these nodules can only be seen on X-rays of the chest areas). The early stages of this affection are characterized by symptoms similar to those of any other respiratory infection, for example a dry cough. This is mainly the cause why Cryptococcosis is not always diagnosed in time, fact that allows various complications to develop. The most common symptoms and signs, specific for this health disorder are: pain felt in the abdominal area or in the chest, tiredness, headache, abdominal fullness felt prematurely after eating, swollen abdomen, nausea and vomiting, loss of the appetite, excessive and unusual sweating over the night, weakness, pain felt along the path of a nerve, bleeding, weight loss, tingling and numbness, confusion, ecchymoses (bruises), petechiae (skin rashes, pinpoint red marks), swollen glands, fever, pain, diplopia (double, blurred vision), dizziness,  abnormal gait, tenderness of the sternum (bone of the breast), encephalitis and irritability.

Cryptococcosis Treatment

You should contact your health care provider as soon as you notice the symptoms specific for Cryptococcosis, especially if you know you have a weak or damaged immune system. It is very important to do this step because if complications appear, this disease represents a real threat for your life. If it is not discovered in time it can lead to complications, such as meningitis, side effects of the drugs, relapses of the infection and permanent damage to the brain and nerves. Those specialists who interact very often with patients with AIDS are more experienced in diagnosing this disorder. The test to determine if a person has Cryptococcosis is very simple and consists in a sample of the CSF (cerebrospinal fluid) and blood that will be examined to see if there is an antigen that is produced by C. neoformans. The sample of CSF is taken during a lumbar puncture from the space between the spinal cord and the vertebrae. After the liquid is withdrawn, India ink is added to observe the presence of the fungus. If it exists, the ink will cover the edges of the fungus or will bind to the capsule. This test is done especially when the patient is asymptomatic, has advanced AIDS and he or she was exposed to the fungus.  Other ways of testing for Cryptococcosis: isolation of the fungus in cultures of CSF, bronchoscopy, cultures of sputum or biopsy of the lung’s tissues. Before proceeding with any treatment it is very important to see how damaged the lungs are. Very useful in this matter are the X-rays of the chest. Urine can also provide a significant result before giving the final diagnosis. If the infection is heavy, the cultures of blood may be positive. Cryptococcosis is usually treated with amphotericin B (desoxycholate) because this is the only medicine that produces a benefic response. Since this drug was discovered, the survival rate reached even to 85-90%. Before this medicine had appeared on market, very few survivors to Cryptococcosis were reported all over the world. Other effective medicines that have decreased the mortality rate are the azoles, flucytosine and Fluconazole. In combination with the last one, amphotericin B is even more effective. All these drugs are used only in persons with a damaged immune system because in those who benefit from a healthy organism, the disease cures itself. Amphotericin B is known to be a very strong drug against fungal infections, although it presents many potentially toxic side effects. For example, the concentration of hemoglobin in the blood may decrease and kidney toxicity may appear. When using this medicine, some patients may accuse fever, nausea and vomiting, muscle aches, chills, headache and diarrhea. This therapy is administrated for 15 or 30 days.



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49 Cryptococcosis Medication Reviews

: 85.71%  (42)
: 12.24%  (6)
: 2.04%  (1)
2 star: 0.00%  (0)
1 star: 0.00%  (0)

Most Helpful Customer Reviews

 
555 of 676 people found this review helpful:
5.0 out of 5 stars Diflucan Online Order
   By (CA, United States)
  Customer since 5/25/2008 - (9 orders)
  Ordered from
  Ordered Diflucan

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Hi, my name is Gwen and I live in Los Angeles and I am going to review my most recent with PharmacyEscrow.com. First, I want to say I give this order a rating of 5 stars. This is probably the fifth time that I have ordered through PharmacyEscrow.com and I placed two drug orders this time that I was ordering. One was for Fluconazole or Diflucan as it is known in the US, 20 tablets of 100 MG each and I believe that came from the Indian pharmacy and then, the second thing I have ordered was 2000 International Units, well, 3 bottles of 2000 International Units each of UNI HCG and I believe that came from Singapore pharmacy. Now, overall, like I said I give it a 5. The delivery was super speedy this time. I paid for normal delivery but it came within a week. I think I placed my order on April 26th and everything, since they were coming from two pharmacies; they came a day apart but around May 7th. So, a week and a day later, pretty much. It was awesome. This was the first, the one negative thing that I would say about this order. It’s the first time I had to do the medical review from the pharmacist or from the doctor and I had to pay $4.99 USD for that and I‘ve never had to do that before with any of my orders which, you know, is not that bad. It’s only $5 USD which is nothing compared to actually going to see a doctor here in the US with or without insurance. So, it’s not that big deal but it was kind of surprise and I will be upset if, you know, I go to order in the future and I have to pay that yet again for another medical review even if I am ordering the same drugs but that’s okay. I still give it 5. The HCG that I’ve ordered from the Singapore pharmacy, the UNI-ZY 2000 IU, each came in a little bottle like this. I’m very pleased with having ordered this the way I did. I think this is the third or fourth different brand of HCG that I’ve ordered and they are all very comparable. They are all low priced, they are all very potent, they are all work for weight loss which is what I use it for but I’m really pleased with this because coming in 3 bottles, you only mix one at a time. So, it keeps its potency. You know if I would have mixed that same amount, one big batch in the beginning, it would completely lose its potency by the end of my round. So, very pleased with getting 3 little bottles. Now, the Diflucan, the Fluconazole, this is the first time that I have ordered and/or taken this drug and it is anti fungal that I am using to treat Candida overgrowth in my system and it’s been wonderful. It’s definitely a potent very intense drug. You have to make sure you’re taking care of your liver at the same time because basically, what’s it’s gonna do is kill all of the Candida, all of the fungus that you have growing in your body and that’s gonna become toxic waste, that’s you know, circulating throughout your blood streams and you gonna have to release those toxins somehow and if you are not really good about you know, making sure that you’re releasing all those toxins properly, your liver and your kidneys could get very backed up. This drug definitely knocks you on your ass, I mean, it’s very powerful but that’s a good thing because you know its working. Like I said, I ordered 20 tablets and it comes in little blister packs like this. Each little tablet is individually blistered, individually wrapped. It’s sort of a pink tablet; they would be chewable but the instructions which are in English are printed on the back and it says to dissolve it and boiled and cooled water and it actually tastes good. It’s not a disgusting drug. Like I said, it works very well. They would be easy to cut in half if you only wanted 50 MG at a time. Overall, very very pleased with this drug and I will order it again. So, yea, very pleased once again, 5 star rating and looking forward to my next order with PharmacyEscrow. Thanks

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407 of 444 people found this review helpful:
5.0 out of 5 stars 200 Mg Diflucan
   By (CA, United States)
  Customer since 5/25/2008 - (9 orders)
  Ordered from
  Ordered Diflucan

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Hello, my name is Gwen and I’m going to review my most recent Pharmacy Escrow purchase, order. This is probably the seventh time that I have ordered something through Pharmacy Escrow and I’ve always been completely satisfied. I ordered twenty eight capsules of 200 Mg Diflucan or as it is known as Fluconazole. I believe it’s from the United Kingdom pharmacy and I’ve been very pleased with it, it worked incredibly, I’m treating a Candida issue for the over growth of yeast and it has really helped to not get out. It’s a little different than the Fluconazole I’ve ordered before, they came in sort of a tablet that you would dissolve and I really liked that but these capsules are you know, a lot easier than having to do that, super convenient. The only issue I would say with this whole order was, the pharmacy didn’t have them in stock and I had to wait maybe a week or a two. So, normally I get my shipments within one week even if I do the normal shipping method and this time I did normal shipping method and I think I had to wait a week or two before the pharmacy even had the drug and then it was another week on top of that, so, I waited a little longer than usual but still it was within the time frame that was quoted. So anyway, I am very happy with my purchase, I will continue to be a Pharmacy Escrow customer and I would give this 5 out of 5 stars, thanks.

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404 of 481 people found this review helpful:
5.0 out of 5 stars I am a happy customer!
   By (CA, United States)
  Customer since 5/25/2008 - (9 orders)
  Ordered from
  Ordered Diflucan

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Hi, my name is Gwen and this is my video review for my most recent order from PharmacyEscrow.com. This is I think my sixth or seventh or maybe even eighth order that I’ve placed. I’ve always been super happy. Once again I’m a happy customer, I ordered two things this time both were Diflucan or Fluconazole, I ordered 20 tablets of 100mg each, generic from the Indian Pharmacy as well as 3 tablets of the 200mg also generic, also from the Indian pharmacy and once again, my order came super fast, I only need, always pay for the regular shipping and it comes within a week of actually placing my order, so that’s awesome and I’m located in Los Angeles by the way, and ya, I was also very happy with the products that i got, I think I prefer the 100mg over the 200mg. The 100mg come in little foil packets and it’s a little dissolvable pink tablet that you know, you dissolve in a tablespoon of purified water and it actually tastes really good, it tastes kind of sweet, so, it’s like a nice little I’m taking my medicine treat. The 200mgs are just a swallow able tablet, they do have a little groove in the middle where you can cut them in half which I did. All around I was very pleased, I can really feel the potency of these anti fungal medications, you can really feel it coursing through your body and you know, really getting rid of whatever fungal infection, I’ve been using them to treat a Candida infection and they are working great, the only thing that I do say is they work so great, you should take a supplement like milk thistle or something to help out your live while you’re detoxifying your body with these but once again, I’m a happy PharmacyEscrow.com customer, so, thank you

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444 of 660 people found this review helpful:
5.0 out of 5 stars High quality products, reasonable prices
   By (WV, United States)
  Customer since 5/23/2007 - (7 orders)
  Ordered from
  Ordered Diflucan

The order was received in a timely fashion, the medications are of high grade, and were received in their original pharmaceutical company packaging. The products are effective, and unlike many online services, the medications I received from your company are 100% real.

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250 of 414 people found this review helpful:
5.0 out of 5 stars Couldn't be Happier with Service
   By (ON, Canada)
  Customer since 9/22/2008 - (2 orders)
  Ordered from
  Ordered Diflucan

These people clearly know what they're doing and do it quite well. To illustrate their diligence: 1) I received prompt notification every step of the way (ie. for order confirmation, order being filled at the pharmacy, shipping, customs, etc.)
2) The guarantee that they'll refund or reship if you have a problem receiving the order simply meant that I wasn't obsessing over where my order was at each and every moment since I knew I could always get my money back.
3) The medication is the same strength and quality you'd find here (in my case, the US)

Overall, I'm very satisfied with the experience and will order from them again if the need arises.

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