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Cutaneous Fungal InfectionCutaneous Fungal Infection – General InformationCutaneous Fungal Infection is a primary or secondary mycotic infection caused by bacteria from the Candida group. This type of disease can have many stages that include acute, subacute and chronic, or episodic. Cutaneous Fungal Infection can appear in many areas such as: the mouth, finger, scalp, nails, bronchi, lungs, gastrointestinal tract, throat, vagina and so on. Candida granuloma is a severe form of the disease, and can develop with endocinopathy, thus causing severe hyperkeratic granulomatous lesions. Generally, the disease develops due to impaired epithelial barrier functions. It can appear in all age groups, but in most of the cases, the newborns and the elderly patients are the most affected. The systemic form of the disease develops in patients with an immune system deficiency or who take a cancer medicine or any immuno-suppression drugs. In most of the cases, the disease is generally caused by a factor such as high exposure to contaminated water. Generally, Cutaneous Fungal Infection is not considered a life threatening condition and is more irritating than dangerous. The disease can be present in many forms such as intertrigo, erosio interdigitalis blastomycetica, diaper rash, candidal balanitis, perianal candidiasis and candidal folliculitis. It is thought that the excessive moisture is the main cause of the disease, but there are many other causes which can include obesity (because obese patients have a big difficulty in keeping the skin dry between the fat rolls), while the other major causes are diabetes and excessive use of corticosteroids.Cutaneous Fungal Infection – SymptomsThe clinical manifestations of Cutaneous Fungal Infection may be episodic, sub acute, acute or chronic. This type of fungus can be found (is located) under the breasts of women, buttocks, on the genital organs, such as the vagina, in the area around the anal orifice, in skin folds, trunk, and in the groin, but may also appear on other areas of the skin. The main signs and symptoms characteristic for Cutaneous Fungal Infection are the following: the existence of some purple patches on the skin (that may be itchy and that resemble very much with an eczema), inflammation and redness of the skin, folliculitis (the infection of the hair follicles) similar to a pimple, blisters that appear around the itchy patches, intense itching, small degree of scaling and rashes or lesions of the skin. Also, some of the patients may complain of enlarging patches, papules (macules) or smaller lesions that usually occur next to the bigger ones – such lesions are called satellite lesions. This skin disorder affects all the age groups, although it is more common among the elder ones and newborns. Furthermore, in people who work in wet conditions, the fungus may cause a severe reaction of the nails, making them crumble. If the patient has a seriously damaged and compromised immune system, the disease can spread on to the entire body, thus causing fatal and really dangerous health problems to the individual.Cutaneous Fungal Infection – TreatmentThe diagnosis for the Cutaneous Fungal Infection is based on medical tests that are made on samples of the patient’s surface of the skin, taking in consideration the risk factors to which the individual has been exposed. In most of the cases the disease can be treated with several antifungal medicines prescribed as clotrimazole, Econazole, Ciclopirox, Miconazole, ketoconazole or Nystatin. The treatment of the Cutaneous Fungal Infection depends on the disease’s cause. If the infection is a bacterial one, the available treatment is a trial with Fluconazole or Itraconazole, administered orally. For the severe form of the disease, called Candida granuloma, the treatment consists in two treatment trials. One involves a dose of Itraconazole that should be taken every day for five months, and the other one consisting in a pulsed dose that should be taken daily for seven days followed by a treatment pause of about 21 days. Obese patients can try to lose weight to clear the problems, and individuals suffering from diabetes can try to control their sugar levels. The most important way to treat Cutaneous Fungal Infection is to keep a general healthy hygiene. Each patient has to maintain his skin dry and he must expose it to fresh air as much as possible. There are cases, in which the doctor recommends a systemic treatment with azoles (an agent containing two groups of compounds, imidazoles and triazoles). For Cutaneous Fungal Infection, the main treatment aims to control the excessive moisture and friction, which can lead to local skin maceration. In these cases the doctor has to prescribe a treatment consisting in a topical imidazole trial that generally proves to be very effective. There are cases in which this treatment is administered in combination with a topical steroid called hydrocortisone. For the oral form of the Cutaneous Fungal Infection, the main treatment is a therapy with Nystatin, administered orally, after meals. While type of treatment is usually used in infants, for the older patients a dose of amphotericin B proves to be very effective. For the vaginal form of the disease, azole creams are usually used to achieve a fast improvement, but doctors usually prescribe the treatment with Fluconazole, thus increasing its effectiveness in almost all the cases. For the neutropenic patients who suffer from this type of disease, the doctor usually prescribes treatment trials with amphotericin B in high doses like 1.0 mg per day, in combination with another medicine called Flucytosine that should be administered in doses of about 150 mg per day. There are many treatment options that can be applied to treat this type of fungal disease. For the immuno-suppressed patients it can be impossible to correct the underlying predisposing conditions which caused the disease. In these cases the doctor can prescribe an oral treatment with Fluconazole in100 to 400 mg per day doses for about two weeks. This type of treatment can also be applied in patients who suffer from the oropharangeal form of the disease. Usually, the disorder can be easily prevented by keeping a general hygiene or maintaining the skin dry as much as possible. |
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