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Dermatomyositis

Dermatomyositis – General Information

Dermatomyositis is a tissue disease which is characterized by inflammation of the muscles or the skin. This type of disease is also considered a systemic disorder, which can also affect the esophagus and lungs and, less commonly, the heart. The complications of this disease are rare, and the most encountered form is called calcinosis. This is a complication that appears most often in children or adolescents. Dermatomyositis can develop at any age, but the most affected are the adults with the age between 40 and 60 years old or young patients with the age between 5 and 15 years old. The appearance of the disease is most common in women than in men. This kind of disease usually takes over weeks or months to develop and it causes no signs and symptoms. Then the symptoms improve spontaneously. This medical condition has a very high risk of recurrence. There are many treatments available to improve the skin appearance or the strength and function of the muscles. When the skin is affected, the main treatment options are sun avoidance, sunscreens, topical corticosteroids, antimalarial agents, methotrexate, mycophenolate mofetil and intravenous immune globulin. But when the muscle is involved, the main treatment option is the one consisting in corticosteroids, used sometimes in combination with an immunosuppressive agent therapy. Dermatomyositis is categorized as an inflammatory myopathy. Myopathies usually affect the muscles. The cause of these inflammatory myopathies is still unknown, but some doctors say that the disease can also be considered an immune system disorder.

Dermatomyositis – Symptoms

The signs and symptoms of the Dermatomyositis disease depend on the type of the tissue that has been affected. If the skin is affected the main sign is the violet colored or dusky red rash, which appears usually on the face, eyelids, and areas around your nails, knuckles, elbows, knees, chest and back. These areas become more sensitive to sun exposure. But if the muscle tissue has been affected, the main sign is muscle weakness, and the affected areas are the ones surrounding the trunk. They can include hips, thighs, shoulders, upper arms and neck. The weakness sensation is considered symmetrical because it affects both the left and right sides of the body. There are also some specific signs and symptoms of the Dermatomyositis disease. They can include difficulty swallowing, a condition called dysphagia, muscle pain or tenderness, fatigue, fever and weight loss, hardened deposits of calcium under the skin, called calcinosis, encountered especially in young patients, gastrointestinal ulcers and infections, which are also more encountered in young patients and, sometimes, lung deficiency. In most of the cases, the skin signs appear at the same time with the muscle weakness, but there are cases in which the skin rash appeared several weeks after the muscle symptoms had developed. These signs are the main criteria in determining the diagnosis. The muscle weakness, affecting the hips or shoulder, can cause the difficulty in climbing stairs, getting out of a chair or brushing the hair. In severe cases of Dermatomyositis, the muscle weakness can lead to difficulty in holding the head up.

Dermatomyositis – Treatment

Generally, there is no cure for the Dermatomyositis disease, but the available treatment option can improve the appearance of the skin, the strength and function of the muscles. If the treatment is started in an early stage of the disease it proves to be more effective, because later on, without treatment, the disease tends to develop severe complications. The treatment options can include corticosteroids, immunosuppressants, antimalarial drugs or physical therapy, surgery and pain relievers. The corticosteroids treatment reduces the skin or muscle inflammation by suppressing the immune system, which reduces the secretion of antibodies. The most common corticosteroid prescribed by the doctors is Prednisone. In most of the cases, at the beginning of your treatment with corticosteroids, the doctor administers you a high dose, which can be decreased if the signs and symptoms of the disease improve. To achieve visible improvement of the skin, the treatment with this medicine has to be taken at least six months, but there are cases in which the therapy can be used for many years. If the corticosteroids therapy is applied for a long term, it can lead to the appearance of severe side effects which can include osteoporosis, weight gain, diabetes, vulnerability in developing infections, mood swings, cataracts, high blood pressure, a redistribution of body fat and muscle weakness.

To prevent the appearance of such side effects, doctors usually prescribe food supplements such as calcium and vitamin D, bisphosphonates, alendronate prescribed as Fosamax or risedronate as Actonel . Another therapy for Dermatomyositis disease is the one using immunosuppressants. The most common prescription drugs are Azathioprine or Imuran and Methotrexate or Rheumatrex , which are applied if the patient’s body resists to the corticosteroid therapy. There are cases in which the immunosuppressants medicines are used in combination with corticosteroids, and prove to have fewer unpleasant side effects. To improve the symptoms caused by the Dermatomyositis, doctors can also prescribe immunosuppressants such as cyclophosphamide as Cytoxan and cyclosporine as Neoral or Sandimmune.

When the patient experiences symptoms like persistent rash, the doctor can recommend antimalarial drugs to treat it. The common antimalarial medicines are hydroxychloroquine prescribed as Plaquenil and chloroquine phosphate prescribed as Aralen. Physical therapy plays an important role in treating Dermatomyositis. By applying this type of therapy, the patient can improve his strength and flexibility of the muscles. Keeping a generally active condition is essential for such patients. When the patient experiences the pain caused by the build up of calcium deposits, the main treatment option is the surgical approach, used to remove these deposits. Another way to treat Dermatomyositis is the pain reliever therapy. The most common pain relievers recommended by the doctors are aspirin, ibuprofen prescribed as Advil or Motrin, and acetaminophen prescribed as Tylenol. If the pain persists after the administration with these medicines, the doctor can recommend a stronger pain reliever called codeine. There are many other procedures that are theoretically effective and consist in plasmapheresis, which is a plasma exchange, radiation therapy and so on. 




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8 Dermatomyositis Medication Reviews

: 62.50%  (5)
: 37.50%  (3)
3 star: 0.00%  (0)
2 star: 0.00%  (0)
1 star: 0.00%  (0)

Most Helpful Customer Reviews

 
216 of 388 people found this review helpful:
4.0 out of 5 stars Most satisified
   By (Kanagawa-Ken, Japan)
  Customer since 4/14/2008 - (7 orders)
  Ordered from
  Ordered Methoblastin

I was most impressed with the ordering process since it was my first time to use PharmacyEscrow.com. Once I had answered all of the registration questions and submitted the particulars for my condition, it was very easy. The staff were very sincere and understanding of my situation - my medication is unavailable in the country where I am now living, so it is imperative that I get my medications this way. The medication came through in reasonably good time, although I think one med was actually out of date and the company kindly re-sent the order and credited my account with a discount on the next order. Finally, I was most satisfied with the packaging and condition of the products upon arrival.

Great stuff

mark

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114 of 196 people found this review helpful:
5.0 out of 5 stars Very positive -extremly fast delivery
   By (Warszawa, Poland)
  Customer since 1/15/2005 - (10 orders)
  Ordered from
  Ordered Plaquenil

I placed an order in the US, shipping address was in Europe. My order was completed in 2 weeks although my medicine was send from India.I was impressed.

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114 of 205 people found this review helpful:
5.0 out of 5 stars Positive- easy to order, good quality, fast shippping
   By (Warszawa, Poland)
  Customer since 1/15/2005 - (10 orders)
  Ordered from
  Ordered Plaquenil

It is very easy to place an order. I usually order generics. There is no difference between original brand and generic. Last time delivery time was improved and I have got my medicine very fast. Pharmacyescrow.com staff usually informs when the ordered medicine is send to the customer

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83 of 161 people found this review helpful:
4.0 out of 5 stars Positive - good product, quite good shippment
   By (Warszawa, Poland)
  Customer since 1/15/2005 - (10 orders)
  Ordered from
  Ordered Plaquenil

It is very easy to place an order. Product is OK. Quite fast shipment if you take into account that product comes from India. Good communication with the company

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3 of 6 people found this review helpful:
5.0 out of 5 stars Plaquenil (Hydroxychloroquine)
   By (WV, United States)
  Customer since 10/14/2010 - (1 orders)
  Ordered from
  Ordered Plaquenil

This medication was better quality than what I got here at my pharmacy. It worked better, I felt less tired taking this than the medication supplied directly from my doctor. So happy with this medication. I was feeling horrible until I started using this. I felt half my age afterwards. I would not hesitate to come back again to this pharmacy with any prescription needs. Price was very reasonable. Time to arrive is fair. I would definitely recommend this to any family member or friend.

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