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Gastroparesis

Gastroparesis – General Information

Gastroparesis is considered a condition in which the patient’s stomach muscles do not work as they are supposed to. In general, the stomach muscles contractions should help the consumed products to be transformed inside the patient’s gastrointestinal tract. In patients who suffer from Gastroparesis, their stomach muscles work poorly and can even not work at all, which causes the premature fullness. This process can also interfere with the digestion, leading to the appearance of symptoms such as nausea and vomiting. These can cause deficiencies in the blood sugar levels and nutrition. There are many risk factors that can lead to the appearance of this kind of disease and can include diabetes, which is the main risk factor. Studies show that at least one in five patients suffering from diabetes develop the disease. Other risk factors include taking medications to slow the rate of stomach emptying, having abdominal surgery, taking certain cancer treatments and suffering from other medical condition that can affect the stomach nerves or muscles. In general, there are no treatment options that can cure this medical condition - Gastroparesis. The treatment options can consist in dietary changes or certain drugs that act by controlling the signs and symptoms, but there are cases in which these medications are ineffective. The majority of medicines that are used to treat the disease can also cause severe side effects. Surgery can also be applied as last measure if the other treatments have failed. It is very important to treat the disease in an early stage to prevent the appearance of other more severe complications.

Gastroparesis – Symptoms

This kind of disease can be caused by several risk factors which can include medications, such as tricyclic antidepressants and calcium channels blockers, cancer treatments or surgery on the esophagus, stomach or parts of the patient’s intestine. Gastroparesis can also develop from other conditions such as diabetes, which is the main cause, anorexia, bulimia, Parkinson’s disease and many other nervous system conditions. The most encountered signs and symptoms of the Gastroparesis disease can include nausea, vomiting or a sensation of fullness after eating very little, sensation called early satiety. There are cases in which the vomiting can appear after several hours after the patient has ate, especially when his stomach is still full with the undigested products and with the normal stomach secretions. In some cases, only the accumulation of stomach enzymes and acids can cause the vomiting symptoms, even if the patient does not eat. Generally, the stomach muscles are classified in several categories depending on the foods (solid or liquids) and that is why the patient who suffers from Gastroparesis has difficulty in digesting solid products, or a combination of solid and liquid foods. In some cases, in addition to the common signs and symptoms of vomiting, nausea and premature fullness, the disease can cause some rare signs and symptoms such as abdominal bloating, heartburn or gastroesophageal reflux, changes in the patient’s blood sugar levels, lack of appetite and weight loss or malnutrition. It is very important to treat the disease in an early stage to prevent any severe complications.

Gastroparesis – Treatment

The main goal of the treatment used to treat Gastroparesis is to control the condition, usually diabetes that has caused the disease. The treatment options can include dietary changes, medications, used to increase the stomach contractions, and surgery. In some cases, the medication treatment causes severe side effects and is not always effective and that is why doctors try to apply less conventional treatments. In most cases, doctors recommend dietary changes to treat Gastroparesis. They can include smaller, more frequent meals, which helps to avoid the fullness sensation, low fiber products, which helps whisk the food through the intestinal tract, low fat products, pureed and liquid products, nutritional supplements, which can supply with the missing nutrients in the meals, water, because the vomiting from the disease can lead to dehydration. There are cases in which the patient can suffer from stomach problems and can not tolerate the liquid products, and the only way to consume them is by a jejunostomy tube placed in the small intestine. In most cases, this tube is inserted directly through the skin into the patient’s small intestine, but it can be used as a temporary nasal and oral tube. The jejunostomy tube is used in severe cases of Gastroparesis, in which the patient’s blood sugar levels can not be controlled by another treatment option.

The medication therapy, in most cases, includes two types of drugs such as anti emetics, which can be prescribed as prochlorperazine and are used to control the symptoms of nausea and vomiting, and prokinetics, which are used to stimulate the contraction of the stomach muscles. The main form of drug administration is the pill, but in some cases the capsules can not be absorbed and that is why doctors can prefer injecting them or administrating them in a liquid form. The most used prokinetic medicines can include Metoclopramide, erythromycin and cisapride. Metoclopramide is a prokinetic medicine that is used to lower the pressure threshold for the peristalsis reflex, to increase the strength and frequency of the muscle contractions and to relax the pyloric valve that allows the food to pass from the stomach to the patient’s small intestine. It is also used to control the symptoms of nausea and vomiting. Erythromycin medicine is not considered prokinetic, but it is rather used as an antibiotic which is applied to produce short bursts of the strong stomach contractions. The medicine is rarely used because it can cause several side effects such as nausea, vomiting, diarrhea and hearing loss. In some cases, the medicine can worsen the patient’s signs and symptoms. Cisapride is used in severe cases of Gastroparesis, and is usually contraindicated in patients who suffer from heart or kidney dysfunctions because it can cause fatal heart arrhythmias. There are cases in which the doctors can apply the surgical approach to treat Gastroparesis. The surgical procedure is made when the other treatment options failed to relieve the severe symptoms of nausea, vomiting or malnutrition. The procedure consists in removing the lower part of the patient’s stomach to improve the stomach emptying.




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4 Gastroparesis Medication Reviews

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Most Helpful Customer Reviews

 
189 of 350 people found this review helpful:
5.0 out of 5 stars Very good!
   By (Overijssel, Netherlands)
  Customer since 7/10/2008 - (15 orders)
  Ordered from
  Ordered Reglan

I had a stomach problem an enjoy this product. My stomach problem is away !! 3 pills a days and everything is alright.

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93 of 164 people found this review helpful:
5.0 out of 5 stars First order!
   By (GA, United States)
  Customer since 7/31/2007 - (3 orders)
  Ordered from
  Ordered Reglan

My first order with them here, No problems at all. I recommend!! service and quality GREAT, I am impressed and will be back! Thank you!

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6 of 12 people found this review helpful:
5.0 out of 5 stars Excellent service
   By (TX, United States)
  Customer since 1/21/2011 - (7 orders)
  Ordered from
  Ordered Reglan

I was kept informed of the order status from check out to delivery. The order was filled quickly, accurately and shipped when promised.

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6 of 15 people found this review helpful:
5.0 out of 5 stars Good product
   By (Victoria, Australia)
  Customer since 4/18/2009 - (35 orders)
  Ordered from
  Ordered Reglan

The product is the original Maxalon that I used to buy when I was overseas. It arrived in pristine in good conditions and on time. I take it when I need it and it works perfectly. When I moved to Australia I used to ask my sister to send it by post from overseas. Then I found this option which is actually much cheaper and faster. The rating is well deserved given that my life is much simpler and I do not to see a doctor every time I need a new box. I just buy online and I get it in a couple of weeks. What do you want more?

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