Hemorrhagic Cystitis Prophylaxis

Hemorrhagic Cystitis General Information

Cystitis is a common medical term that defines an inflammatory medical condition that affects the individual’s bladder. In most clinical cases, the presence of this medical affection is a direct consequence of an infectious medical disorder that is located in the patient’s urinary tract system. Although in most cases the urinary tract infection is actually caused by a bacterium, in other clinical cases, the cause of the infectious disorder is one of the following: reaction to a prolonged therapy with a certain medicine, radiation therapy, potential irritants, and so on.

Scientists define Hemorrhagic Cystitis as the unexpected onset of hematuria (blood in the urine). This is generally accompanied with other irritative bladder symptoms such as bladder pain. The amount of blood that is found in the patient’s urine is known to generally range from mild to severe, depending on the stage of the patient’s cystitis. The developing of this medical condition is generally unexpected, as Hemorrhagic Cystitis may occur during a therapy, immediately after a certain therapy option or a couple of months after a therapy. Although this medical condition can be quite severe as it may lead to life threatening infectious medical disorders (such as urosepsis) or to severe hemorrhage (loss of blood), in most cases, the patients have successfully recovered from it.

Hemorrhagic Cystitis Prophylaxis

In this part of our article, we aim to familiarize you with a set of Hemorrhagic Cystitis Prophylaxis options that may help you prevent developing this unpleasant medical disorder. The most effective medical options include the following: one should continuously irrigate his or her bladder with normal (healthy) saline; an aggressive therapy that involves massive fluid intake (this can be achieved either orally or intravenously) is recommended as it is able to flush the unneeded metabolites from the patient’s bladder; the use of diuretic medicines may help the patient alkalinize his or her urine (if necessary); such medicines should also be prescribed in their IV form for those who present an abnormally low urine output; in some cases, the use of Mesna (a special substance that is able to protect the lining of the patient’s bladder as it effectively binds to acrolein – a metabolite, forming an inactive compound that can be easily excreted from the patient’s bladder without further help – the use of this medication does not affect the anti-cancerous activity of any potential chemotherapy that the patient may undergo. These are some of the most common Hemorrhagic Cystitis Prophylaxis measures that should prevent you from becoming infected with this medical condition.

Furthermore, we will present you a short list that includes the most common risk factors that are known to be able to make an individual experience the hemorrhagic form of this bladder infectious disorder – as we consider that being well acquainted with the most common risk factors is an important part of the Hemorrhagic Cystitis Prophylaxis. The most widespread risk factors include: the use of chemotherapy remedies (especially Ifosfamide, Cyclophasphamide, and so on), undergoing pelvic radiation therapy (especially if it is accompanied by chemotherapy), medical history that includes the presence of bladder cancer, the use of antibiotic remedies, persistent urinary tract infectious disorders, low platelet count (an condition also commonly known as thrombocytopenia), undergoing bone marrow transplant, the presence of various types of viruses (especially adenovirus, papovarius, and so on).

Hemorrhagic Cystitis Treatment

If an individual is diagnosed with the presence of this bladder infectious medical disorder (commonly referred to as Hemorrhagic Cystitis), he or she should receive immediate professional medical care, as this type of infectious condition can easily spread further in the urinary tract (it can reach the patient’s kidneys). Vaginal penetration should be avoided by females who are suffering from this condition until the infection has been completely removed, in order to prevent experiencing any severe complications.

There are various therapy options that can be employed in the case of patients who are suffering from this type of cystitis. Although there is no established therapy protocol that should be effective against this infectious medical condition, most treatment options aim to ease the individual’s symptoms and to deal with the infection. For this reason, individuals who are diagnosed with the presence of Hemorrhagic Cystitis will probably be prescribed an antibiotic therapy accompanied by an adjacent intake of analgesics (pain relievers). In case the patient develops anemia due to severe bleeding, blood transfusions may be necessary. In the most severe cases, individuals have received instillation of certain medical products into their bladder in order to stop or at least control the bleeding. In some cases, the physician may decide to prescribe the patient prophylactic low doses of a certain antibiotic even after the acute clinical manifestations of the infectious disease have subsided.