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Hypokalemia

Hypokalemia – General Information

Hypokalemia is a quite common medical condition that means that the patient’s blood levels of potassium are too low. This electrolyte (potassium) is extremely important for the human organism as it is supposed to enable the contraction of the smooth and of the skeletal muscles, the conduction of the nerve impulses, and so on. The presence of this electrolyte in the blood is also crucial as it facilitates the normal enzyme activity and the function of the cell membrane. This is why it is of high significance for the patient to maintain a homeostatic (proper) balance of his or her potassium blood levels in order to maintain a well general health condition. The healthy concentration of potassium in the patient’s serum usually ranges between 3.5 and 5.0 mM. Patients who have been diagnosed with Hypokalemia regularly present less than 3.5 mM of potassium in their blood. Studies have shown that the cause of this medical condition can be the excessive uptake of this electrolyte by the organism’s muscles (in such cases, the condition is only temporary) or by the overall depletion in the organism’s potassium (in this case, the disorder is generally a chronic medical condition). The average adult patient who weighs about 70 kg ought to have approximately 3.6 moles of the ions of this electrolyte in his or her body. It has been shown that 98% of the body potassium is found inside various organs and / or cells. Only 0.4% of the amount of potassium that is located in the patient’s blood serum.

Hypokalemia – Symptoms

Like most other medical conditions, Hypokalemia is known to generally trigger a variety of symptoms and / or signs that enable the physician diagnose the patient. While the mild forms of this medical disorder do not trigger any severe symptoms, patients who have been diagnosed with the moderate to severe types of this disease complain of several unpleasant reactions. For example, individuals with a moderate Hypokalemia are known to present muscular discomfort, muscle weakness, disorientation, confusion, cramping during physical exercise, and so on. Other patients presented limb (leg) discomfort while sitting down that is described as an annoying sensation. The muscular discomfort is easily eased with some simple methods: stomping of the leg on the floor, shifting the position, and so on. A patient is diagnosed with the moderate form of this medical condition if his or her potassium levels are between 2.5 and 3.0 mM. Patients with the most severe forms of Hypokalemia are known to widely complain of extreme fatigue, abnormal weakness, and, in some cases, paralysis. This last symptom is also called limpness or "flaccid paralysis”. This is a very severe reaction, as lung paralysis is a potentially lethal symptom. But there are other dangerous signs that are present in similar clinical cases (in patients who were diagnosed with a severe lack of potassium). For example, studies have shown that abnormally low levels of potassium can affect the individual’s heart rate, causing arrhythmia. This syndrome is also life-threatening, as cardiac arrest can easily occur (in such clinical cases, the heart simply stops beating). A patient is diagnosed with the moderate form of this medical condition if his or her potassium levels are lower than 2.5 mM.

Hypokalemia – Treatment

The patient’s potassium levels can easily be measured – the individual has to undergo a simple blood exam. During the clinical test, a special electrode (that is sensitive to potassium) is employed, as it can effectively measure the concentration of the ions of potassium. Another way to adequately measure the individual’s potassium ion concentration involves a procedure called atomic absorption spectroscopy. As a patient who is suffering from Hypokalemia often presents abnormalities in his or her heart functions, another way to diagnose this medical condition involves a clinical test called electrocardiogram. The patient’s urine can also enable the physician determine whether the patient indeed has this medical condition (and to see whether the individual presents the mild, the moderate or the severe form of Hypokalemia), as if the potassium concentration from the patient’s urine is less than 25 mM per day, the individual has probably experienced abnormally high losses of this electrolyte through diarrhea. This test (the urine test) is considered extremely useful especially when the individual does not admit that he or she is practicing enema or laxative abuse. However, if the patient’s low levels of potassium were caused by the intake of diuretic medicines, the individual’s urine will contain a much higher concentration (more than 40 mM per day).

If a patient has been diagnosed with the severe form of Hypokalemia, he or she should be immediately placed on a cardiac monitor. Physicians ought to assess his or her respiratory status at once. The first therapy option involves the IV (intravenous) administration of this electrolyte (potassium). However, less severe forms of this medical condition are treated with oral potassium supplements. Most potassium supplements that are available on the market are known to also contain KHCO3 (potassium bicarbonate), KCl (potassium chloride) and even potassium acetate. The most effective therapy option for patients who present the mild form of this disorder involves the intake of potassium chloride, as studies have shown that this is the safest and fastest treatment. Most clinical cases in which the disorder was due to a prolonged therapy with diuretics are prescribed 40-80 mM of KCl in daily doses. However, all patients ought to be aware of the fact that not every individual who is following a therapy with a diuretic will suffer from Hypokalemia. This medical condition can be easily avoided if the patient follows a healthy diet that contains foods that have high amounts of potassium. In most cases, the average prognosis for patients who present Hypokalemia is great. However, in the most severe cases of low potassium levels, the physician ought to be extra careful as not to prescribe the patient an abnormally high amount of potassium as this can lead to severe complications. If you want to know more about this medical condition, we strongly advise you to refer to your personal health care provider, as this article contains only a set of basic information about this disorder.




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