Niacin Deficiency

Niacin Deficiency – General Information

This Niacin Deficiency is unusual in highly-developed countries. Niacin is an indispensable vitamin which sustains the metabolism and the reactions that involve biosynthesis and debasement as a sequence of the NAD (nicotinamide adenine dinucleotide), the pyridine nucleotide coenzymes and the NADP (nicotinamide adenine dinucleotide phosphate).The degree of the reduced and oxidized coenzymes sets the redox potential and controls the metabolic activities. Niacin can be created in the body from the important amino acid tryptophan. The transformation of this acid into niacin requires the existence of certain nutriments, like iron, vitamin C, thiamin, and Pyridoxine. The two coenzymes which are formed by niacin are involved in numerous metabolic reactions. They take out energy from glucose and carbohydrate, they help creating steroids and red blood cells, and they synthesize the fat acids and assist the metabolism of certain toxins and drugs. To sum up, niacin is indispensable for the coenzymes which provide energy to the cells; it is also important as it rushes circulation, keeps the brain activity at a healthy level and reduces cholesterol. Vitamin B3 assures the well-being of the tissues belonging to the digestive tract, skin and tongue and it is essential for the chemical process of producing sex hormones. The Niacin Deficiency usually appears in the territories where people eat maize as regular food. This happens because the niacin is attached to the maize so strongly that the body does not have access to it.

Niacin Deficiency – Symptoms

Niacin Deficiency – Treatment

In order to treat this Niacin Deficiency you will be prescribed supplements of vitamin B3 and proteins for helping you to reach an appropriate level of amino acids. Taking these supplements with food may decrease the stomach pain and the danger of ulcer. The dosage is going to be increased gradually in order not to cause side effects or the damage of the skin tissues. An adult should take between 15 and 20 milligrams daily and should not get beyond 40 milligrams under any circumstances. Children suffering from Niacin Deficiency are not recommended to take vitamins supplements as there are not enough evidences of the side effects. Although there weren’t any serious problems the effectiveness and safety are not clearly defined. In these conditions, the best treatment for children is a dietary alteration. When you begin the treatment you may experience various sensations of warm on the neck, face and ears but this is just a mild reaction. You can reduce these side effects by taking drugs against inflammation, such as naproxen or ibuprofen. When you decide to start the therapy for treating Niacin Deficiency you could go through nausea, stomach disorder and vomiting.

More serious reactions to the supplements of vitamins include stomach ulcer, liver toxicity an increased level of liver enzymes in the body cells. Another problem of taking niacin is the alteration it provokes to the level of sugar and insulin in the body; this is a real concern for the sufferers with diabetes or hypoglycemia who should be permanently supervised. Theoretically, gout could appear while taking niacin supplements because of the increased level of uric acid. Treating Niacin Deficiency with B3 supplements can lead to irregular heart rhythms and an increased level of homocysteine which brings a higher risk of heart disease. Other side effects but which are rarely reported are gum pain, tooth pain, headache, dizziness, anxiety, breathing difficulties and panic attacks. The use of niacin supplements is not recommended to pregnant women or to those who breastfeed their children due to the poor studies in this area. Theoretically, there is a high danger of liver damage if you combine niacin with drugs or alcohol and simultaneous utilization of nicotine and alcohol can increase the niacin- induced flushing. If you suffer of diabetes, the niacin can increase the sugar levels in the blood and this can ask for adjustments of your insulin dozes. Studies show that niacin interferes with the thyroid hormones, on the other hand, birth control drugs lower the dosage of niacin required as they increase the production of niacin in the body. If you suffer of Niacin Deficiency and you take niacin supplements you should avoid dietary supplements and other herbs. Examples regard bee pollen, ackee, borage, butterbur, birch oil, chaparral, and germander. Niacin may alter the results of using herbs like garlic or fish oil in order to lower the cholesterol levels in the blood. Antioxidants can cause a reduction of the effects of taking niacin supplements. If you are following a niacin treatment you should avoid hot beverages as these may aggravate the skin flushing.