Ovulation Induction

Ovulation Induction General Information

Ovulation Induction Symptoms

Any Ovulation Induction stimulates the development of the mature follicles (one or may be more than one) in women who are infertile or do not have ovulation. In women, the ovulation is the factor key of their body. The Ovulation Induction signs and symptoms are mainly the same for a regular ovulation period. The intensity of these symptoms varies from person to person and depends of the organism. They might be mild or severe and you may observe them or not. The ovulation can be actually felt by some women and it manifests by pain in the lower part of your abdomen that lasts from a few minutes to a couple of hours or days. Another condition that appears during ovulation is a "one-sided back ache" also known as mittelschmerz. The cervical mucus also changes its aspect becoming more stretchy, clear or slippery. In an ovulation, the cervix may also change from dry, hard, closed and low to open, soft, wet and high. The symptoms may differ from a normal one because of the side effects of the medicines because all of them have a very high risk of developing complications. Some research proved that the agents that are contained in the drugs represent a real risk to develop ovarian carcinoma that may be a very life-threatening disease. There can appear a rare adverse effect called OHSS (ovarian hyperstimulation syndrome) that manifests with   difficulty breathing, severe pain in the chest, abdomen and pelvis, bloating, nausea, vomiting and weight gain.

Ovulation Induction Treatment

Any Ovulation Induction is based on four types of medications that lead to pregnancy in the case that there are no more causes of infertility and if the woman’s eggs that remain in the ovary have a good quality. In the other case, when the eggs do not have the best quality and the woman has ovarian failure, no drug could possible lead to pregnancy so that the only solution left is an egg donation. If the treatment will have success and if the women will get pregnant depends on her age, health status, the presence of any factors in the couple that may lead to infertility and the type of drug used. The main four therapies are based on injectable gonadotropins, bromocriptine, clomid (clomiphene citrate, serophene) and GnRH pump. All medicines for Ovulation Induction are fertility drugs that help stimulating the follicles from the ovary. The result is a production of numerous eggs during one cycle. To achieve pregnancy, the sexual intercourse, in vitro fertilization procedures and intrauterine inseminations are scheduled after the time of ovulation or the releasing of the eggs, processes controlled by the medications. The substances used in Ovulation Induction carry high risks after them, such as ovarian cysts or an increase chance for high order multiple births. Women who do not have regular menstrual cycles or are very long are receiving a treatment with tablets of clomiphene Citrate.

In Ovulation Induction, the prolactin levels are lowered with parlodel that can also act on the pituitary tumor size, by reducing it. It does not have side effects comparative with the other drugs and it is not very expensive, being taken orally, one with the meals. An injectable medicine is the gonadotropin that induces the releasing of the mature eggs once the follicles are developed. In this type enters Bravelle, Repronex, Pergonal, Follistim and Gonal-F that produce a large variety of side effects that are relieved after the follicular are aspirated. Metformin is a glucophage that reverses the endocrine abnormalities and is given to lower the insulin. It leads to weight loss, regulation of menses, hair loss, diminished body and facial hair growth, normal fertility and normalization of elevated blood pressure. If the Ovulation Induction reaches an aggressive form, it is called superovulation and the treatment is based on a combination of gonadotropins and clomiphene. A close monitored ultrasounds and blood tests ensure that the right dosage is given and that the patient is not hyperstimulated. After the superovulation is finished, the ovulation stimulation is made by lower doses of human chronic gonadotropin (HCG).  The costs of the induction are usually very high, but depend on the dosage and type of drug used and on the number of blood tests or ultrasounds that were required during the monitored cycle. A treatment with Clomid may vary from $200 to more than $700, depending on what the doctor applied as additional therapy. Much more expensive are the gonadotropins that are given intravenously also depending on the other secondary treatments and the dosage needed for the case.