Zyloprim (Allopurinol)

Zyloprim Information

Zyloprim, with the generic name of Allopurinol, works by repressing the production of uric acid in the body.

Zyloprim Indications

Zyloprim is mostly prescribed to patients suffering from or prone to:

• Gout
• Increased levels of uric acid caused by cancer treatments
• Kidney stones caused by high levels of uric acid

Zyloprim Warnings/Precautions

Have a talk with your physician before deciding to take Zyloprim especially if you have kidney or liver disease. You may be given a lower dosage or may need to undergo specific monitoring during the treatment period.

Zyloprim belongs to a class of drugs called FDA Pregnancy Category C. This entails that its effects to an unborn fetus is not certain. It is therefore suggested to see your doctor if you are pregnant before taking this drug.

Nursing mothers are also advised to consult their doctor prior to taking Zyloprim as this passes into breast milk and may be unsafe for the breastfeeding baby.

Zyloprim Intake Instructions

Zyloprim must be taken exactly as directed by your doctor. If there is any instruction in the label that appears unclear to you, ask your doctor, nurse, or pharmacist.

Each dose is taken with a full glass of water on a full stomach. To lessen the chance of kidney stone formations, it is recommended to drink 8 to 10 full glasses (8-ounce glasses) of fluid a day.

Zyloprim Missed Dose

Unless directed by your doctor, Zyloprim must not be double dosed. If you miss a dose, take it as soon as you remember as long as it is not almost time for the next scheduled dose. Otherwise, forego missed dose and proceed with the next one.

Zyloprim Overdose

If symptoms of over dosage are suspected, consult your doctor for the proper medical action.

Zyloprim Side Effects

Stop usage of Zyloprim and seek medical attention if you experience any of the following adverse conditions:

• Allergic reactions such as difficulty in breathing, closing of the throat, swelling of the lips, tongue, face, or hives
• Blood in the urine or painful urination
• Rashes
• Eye irritation
• Fever, chills, or joint aches
• Severe nausea or vomiting

Minor side effects that are more likely to occur include:

• Upset stomach or diarrhea
• Headache, dizziness or drowsiness
• Acute attack of Gouty Arthritis

In any of the cases mentioned above, continue use of Zyloprim and inform your doctor. For other side effects not listed that are particularly causing discomfort or pain, tell your doctor right away.

Zyloprim Drug Interactions

Inform your doctor if you need to take ampicillin (Principen, Omnipen) or Amoxicillin (Amoxil, Augmentin, Trimox, Wymox) while under treatment with Zyloprim as this may likely result to having rashes. Also tell your doctor if you are taking Thiazide diuretics such as hydrochlorothiazide (Hydrodiuril, Hygroton, HCTZ), chlorothiazide (Diuril, others), chlorthalidone (Thalitone, others), or indapamide (Lozol). Diuretics may increase the amount of Zyloprim in the blood.

Other drugs may also have adverse interactions with Zyloprim, such as:

• Azathioprine (Imuran)
• Mercaptopurine (Purinethol)
• Drugs used to cure cancer
• Cyclosporine (Sandimmune, Neoral)
• Chlorpropamide (Diabinese)
• Warfarin (Coumadin)
• Theophylline (Theochrone, Theolair, Theo-Dur)

If you are taking any of the above medications, inform your doctor. You may need to undergo special monitoring or may be given dosage adjustments.

Always have a talk with your doctor prior to taking other prescribed or over-the-counter medicines, including herbal products, while under treatment with Zyloprim.

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