BONEFOS (CLODRONATE DISODIUM)

Bonefos Information

Clodronate Disodium (KLA-dro-nayt) is also known in Canada as Bonefos. This is a drug that can be prescribed to patients who are suffering from cancer. This drug can only be bought with a physician’s prescription.

Bonefos Indications

You should talk to a physician before you start taking this drug.
It may not be advisable to start a treatment with Bonefos in these cases:

• Allergies – If the patient is allergic to this drug or to its ingredients or to foods, dyes or other preservatives.

• Pregnancy – Bonefo’s actions on pregnant women are not known. When tested on animals, this drug has caused birth problems. You should discuss it with your doctor if you are pregnant or are planning to be.

• Children – Bonefos has not been studies on children.
• Other adults – The effects of this drug on elder patients have not been clearly established.

Other medical problems

– If you are following a treatment with Bonefos, you should inform your doctor if you are suffering from any other medical disorders because other diseases could affect Bonefos’ actions. These diseases are:

• Stomach pain or cramping, stomach burning, nausea
• Kidney problems.

If you are suffering from any of these conditions, you should be prescribed a lower dose of Bonefos.

Bonefos Warnings

During a prolonged treatment with Clodronate Disodium (Bonefos) you should make sure that you are drinking plenty of fluids (before, during and after the treatment). You should see your doctor at regular visits in order for him or her to be able to monitorize the way in which your body responds to the treatment (you physician should also check the levels of calcium that are found in your blood).

Bonefos Intake Guidelines

You ought to keep this drug away from the reach of children. An overdose with this drug can have lethal effects on infants. This drug must not be stored in damp places (for example bathrooms or kitchen sinks). You ought to keep this drug away from moisture and heat.
If you have extra amounts of Bonefos and if you no longer need them you should ask your doctor what to do with them. You should not keep outdated Bonefos in your house or at the children’s reach.

Bonefos Dosage

The correct dose of this drug is known to vary from one patient to another. You can either rely on the instructions that are written on Bonefos’ label or you can ask your doctor what is the right dose for you.
Here is a list that contains average doses of this drug. You must not change the dose you’re your doctor has given you without his or her consent.
Average oral dosages:

• If the patient is suffering from hypercalcemia:
• Adults- from 1600 to 2400 milligrams (mg) each day (this dose is normally divided in one or two doses per day), no more than 3200 mg per day. You should try to take this drug at least 2 hours after or before a consistent meal.
• Children- Ask a pediatrician for the correct dose and use of this drug.

Average injection dosage:

• If the patient is suffering from hypercalcemia:
• Adults- an injection with 300 mg per day (the treatment can last from 2 to 5 days, but no longer than a week). If you are suffering from kidney problems, you should take a smaller dose of Clodronate Disodium.
• Children- Ask a pediatrician for the correct dose and use of this drug.

Bonefos Overdose

Symptoms of overdose with Bonefos are: mental or mood changes, convulsions (seizures), urinations problems, muscle cramps, stomach cramps or stomach pain, breathing trouble, abnormal heartbeat.

Bonefos Missed Dose

If you miss a dose of Bonefos, take it as soon as you recall. If it is almost time for another dose, skip the one that you have missed and continue with your dosing schedule. You must not take a double dose of this drug without your doctor’s approval.

Bonefos Side Effects

If you are experiencing any of these rare side effects of Bonefos, you should alert your physician:

• Breathing problems
• Sores in throat
• Mental or mood changes
• Convulsions (seizures)
• Unusual heartbeat
• Muscle cramps (arms, hands, face, feet or legs)
• Problems with urination
• Muscle shaking
• Stomach cramps or pain
• Swelling of ankles, face or hands
• Unusual weakness or tiredness

More commonly known side effects are:

• Diarrhea
• Vomiting and nausea 
• Increased bowel movements

Rare side effects are:

• Mouth irritation
• Cloudy urine

Bonefos Drug Reactions

• If you are taking any of the following drugs, you should not start taking Bonefos (Clodronate Disodium) without your doctor’s approval:

• Antacids (e.g., Maalox, Mylanta)
• Calcitonin (e.g., Miacalcin, Calcimar)
• Mithramycin (e.g., Mithracin)
• Corticosteroids (e.g., Prednisone)
• Iron supplements (e.g., Geritol)
• Calcium supplements (e.g., Tums)
• Phosphate (e.g., found in Ensure, Centrum)
• Loop diuretics (e.g., Demadex, Lasix)

Buy Bonefos

Buy Bonefos through our Online Pharmacy Escrow Service or at any Canada Pharmacy selling Online Prescriptions.
In some countries BONEFOS may also be known as: Ascredar, Clasteon, Difosfonal, Lodronat, Mebonat, Ossiten, Clodronic Acid, Ostac, Clastoban, Lytos, Clodron, Climaclod, Clodeosten, Clody, Moticlod, Niklod, Ossiten, Osteonorm, Osteostab, Loron