PROPYLTHIOURACIL

Propylthiouracil Information

Propylthiouracil is a popular medicine that is able to effectively prevent the patient’s organism from producing high amounts of thyroid hormones.

Propylthiouracil Indications

Propylthiouracil is a well known drug that is generally prescribed to patients who should follow a long term treatment for hyperthyroidism. A treatment with Propylthiouracil is known to ameliorate this medical disorder’s symptoms, preparing the patient for radioactive iodine therapy or for subtotal thyroidectomy. 

Propylthiouracil Warnings

Propylthiouracil is a category D FDA pregnancy drug. Therefore, intake of this medicine during pregnancy could trigger some severe birth defects or complications. You should not start a treatment with this medicine if you are pregnant (you should ask your personal doctor if you may start one). During your intake of this medicine you should use an effective birth control method in order to avoid an unwanted pregnancy (your doctor will probably recommend you condoms or diaphragm). It has been clearly determined that Propylthiouracil’s main components are able to, and do pass into the patient’s breast milk. Female patients who are currently nursing an infant are not allowed to start using this drug (Propylthiouracil) without their personal physician’s approval. Consult with a pediatrician before you give this drug to a child. It is known that both elderly patients and children are more prone to developing this drug’s most dangerous side effects. Children for instance risk developing hepatoxicity, caused by a treatment with this medicine. If your child has any symptoms of a hepatic dysfunction you should stop his or her treatment with this medicine as soon as possible.

If you develop aplastic anemia, agranulocytosis, fever, hepatitis, or exfoliative dermatitis during your treatment with this medicine you should stop using Propylthiouracil at once. You might experience bleeding and / or hypoprothrombinemia. Before you start a treatment with this medicine you should inform your personal health care provider if you are suffering or have suffered from any of these medical disorders: blood disorders, liver disease, any allergic reactions. If any of these apply to your medical history, you might not be allowed to start a treatment with this drug or you might have to use lower doses of this medicine. Your intake of Propylthiouracil should be closely monitored by an authorized health care specialist (he or she will probably ask you to undergo a set of medical exams during your treatment with this medicine).

Propylthiouracil Intake Guidelines

We strongly recommend you to ask your personal health care provider to give you a set of detailed instructions regarding your future intake of Propylthiouracil. Do not deviate from any of your doctor’s directions. If you did not understand some of them you should ask a nurse or a pharmacist for additional and more detailed explanations. In case you want to know more about this drug we advise you to carefully read the drug’s label.

Propylthiouracil should be kept at the average room temperature, away from heat, moisture and / or direct sunlight. We recommend you to store it in a place that cannot be easily reached by either pets or children (in order to avoid unpleasant and possibly dangerous accidents like poisoning). Avoid keeping Propylthiouracil in or near the bathroom or near the kitchen sink. Ask your local pharmacist to tell you how you can properly dispose of any unused medication.

Propylthiouracil Dosage

Ask your doctor to calculate the dose of Propylthiouracil that should suit you best. The correct dosage varies from one person to another, as it depends on a couple of factors. During your treatment with this medicine, your personal health care specialist might want to sometimes change your dose of this medicine, depending on how your body responds to the treatment. Do not alter the dose that you have been prescribed by your physician without his or her consent. You can also rely on the dosage instructions from the medicine’s label.

Adults are regularly initially prescribed 300 mg of Propylthiouracil per day, which are divided in 3 equal doses that should be taken in every 8 hours. Adult patients who are suffering from very large goiters or from severe hyperthyroidism could be prescribed 400 mg/day, but not more than 900 mg/day. Children older than 10 years old are initially prescribed up to 300 mg per day, which they should take in 3 equal doses every eight hours. Children aged between 6 and 10 are not prescribed more than 150 mg per day.

Propylthiouracil Overdose

If you suspect that you might be suffering from an overdose with this medicine we strongly recommend you to seek medical care as soon as you can. Alert your personal physician and your local poison control centre at once. Patients who are suffering from overdose with this medicine (Propylthiouracil) are likely to develop vomiting, nausea, headache, epigastric distress, fever, pruritus, arthralgia, pancytopenia, edema, agranulocytosis and so on.

Propylthiouracil Missed Dose

Propylthiouracil Side Effects

A prolonged treatment with Propylthiouracil could trigger paresthesias; headache; neuritis; drowsiness; vertigo; CNS stimulation; neuropathies; depression; rash; pruritus; urticaria; skin pigmentation; erythema nodosum; lupus-like syndrome; exfoliative dermatitis; sialadenopathy; loss of taste; vomiting; nausea; epigastric distress; nephritis.

Propylthiouracil Drug Reactions

Ask your physician if you may use other medicines while taking Propylthiouracil.

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