KLIOVANCE

Kliovance Information

Kliovance is a medicine based on two active substances, Estradiol Hemihydrate and Norethisterone Acetate, two forms of the female hormones estrogen and progesterone. These hormones are used during hormone replacement therapy in order to maintain the normal hormone levels of the female organism. This serves to prevent or treat the symptoms that may appear during menopause.

Kliovance Indications

Health care professionals may decide to employ Kliovance as part of a combined hormone replacement therapy with estrogen and progesterone, especially since this medicine contains both hormones. Therapy with Kliovance does not cause the patient to have a monthly withdrawal bleeding, thus it is preferred in the case of postmenopausal patients that no longer have their periods – typically patients that have gone through menopause more than 12 months before starting their therapy with this medicine. However, this preparation can also be employed in the treatment of other medical conditions, as well as in order to prevent certain affections from occurring – for example Kliovance may be employed as a second line prophylactic agent against osteoporosis. If you would like to obtain further information regarding the possible uses of this pharmaceutical product, it is best that you consult with your prescriber.

Kliovance Warnings

Kliovance therapy may not be employed by patients that are allergic to any of this drug’s excipients; if you are unsure regarding this matter, it is best to inform the prescriber of any substances you have a hypersensitivity to, including foods, dyes and preservatives. Patients that have a medical history or are currently suffering from breast cancer or other types of hormone-stimulated cancers, endometrial hyperplasia, vaginal bleeding with no known cause, deep vein thrombosis, stroke, heart attack, angina pectoris, hereditary circulatory system disorders, liver or kidney impairment should not receive a treatment with this drug either. Hormone replacement therapy may not be employed during pregnancy or breast feeding.

The Kliovance hormone replacement therapy may cause the patients to become more susceptible to developing breast cancer or to suffer from thromboembolism or stroke. Apart from that, patients following a therapy course with Kliovance may have an increased risk of developing other medical conditions, especially if they have a family or personal medical history of such affections, including diabetes, endometriosis, epilepsy or circulatory disorders. Other past or current medical conditions may also affect the course of your therapy with Kliovance. It is best to you make sure that your prescriber is familiar with your current health state and medical history before he or she prescribes you a treatment with this medicine.

Kliovance Intake Guidelines

Your health care professional will provide you with a set of Kliovance intake directions at the same time with the medication dosage you should employ. These will include the number of daily intakes and the therapy duration, and you should closely follow all of your prescriber’s recommendations in order to obtain the best therapeutic effects from the hormone replacement therapy. If you are unsure regarding any aspect of your treatment, you should ask your prescriber as he or she is able to provide you with specific information.

Kliovance Dosage

The typical Kliovance dosage that is employed during hormone replacement therapy is of one daily intake of the medicine, consisting of a single pill. This may not apply in all cases; if your prescriber has directed you to take a different number of pills or if the number of daily intakes is different, then you should take the medicine as directed by your prescriber. The dosage may vary due to the fact that not all organisms react in the same way to the medicine, and also the initial dosage is calculated by taking into account a number of factors that are specific to your case. You should never use a different Kliovance dosage than you have been prescribed as this may cause the therapy to not have the expected results.

Kliovance Overdose

In case you take large quantities of Kliovance you may become affected by an overdose with this medicine. This may cause immediate adverse effects, such as nausea and vomiting or uncommon or excessive vaginal bleeding – however in some cases no immediate reactions are present. If you have taken too much of this pharmaceutical product or otherwise suspect that you are suffering from an overdose, you should immediately consult an authorized health care provider as serious consequences may occur. In severe cases, emergency medical attention should be sought.

Kliovance Missed Dose

Missing a dose of your medication does not typically cause any detrimental effects, however you should try to avoid this situation as repeatedly forgetting to take your Kliovance doses may cause the therapy to become ineffective. It is common that breakthrough bleeding or spotting appear during the first months of your therapy; these symptoms are also present or exacerbated if you miss one or more doses of your medication. In order to maintain the effectiveness of the treatment, it is best that you take the missed dose immediately when you remember – unless another scheduled intake is almost due. In this situation you are advised to completely skip taking the missed dose and continue with your regular Kliovance administration schedule.

Kliovance Side Effects

The most common Kliovance side effects include spotting, breakthrough bleeding, breast tenderness or pain, weight gain, peripheral oedema, migraine, anxiety and depression, dizziness, changes in the patient’s sex drive or disturbances in the hepatic functions. Other side effects may occur as well, and it is strongly advised to seek the advice of your physician whenever you experience any uncommon effects related to your Kliovance therapy.

Kliovance Drug Reactions

Kliovance may interact with medicines used in the treatment of epilepsy, with rifamycin antibiotics, with barbiturates, protease inhibitors or with St. John’s wort. Other drug reactions are possible as well. For a full list of possible Kliovance drug interactions it is recommended to consult a pharmacist, a nurse or a physician.

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