ARANESP

Aranesp Information

Aranesp is a man-made protein that has been formulated to help a patient’s body produce more red blood cells, thus preventing anemia. If a patient is suffering from kidney failure or simultaneously taking other medications, they should be prescribed a lower dose of Aranesp.

Aranesp Indications

Aranesp Warnings

You should not take this anemia medication if you are allergic to epoetin alfa, darbepoetin alfa, or if you suffer from:

• high blood pressure;
• allergic reactions to animal products;
• allergic reactions to albumin.

Before you start taking this anemia medication, you must inform your physician if you suffer from:

• heart disorder, high blood pressure or congestive heart failure;
• kidney disease;
• a history of heart attack, stroke, or blood clots;
• a clotting or a blood cell, for example hemophilia or Sickle cell anemia;
• cancer;
• seizure disorders (such as epilepsy).

If you suffer from any of the conditions that have been mentioned here, you might not be allowed to take Aranesp or you will be prescribed a lower dose. Darbepoetin alfa (the human made protein) consists of human plasma; therefore it could contain infectious agents such as viruses that may lead to certain diseases. Although the human plasma that has been donated is tested, screened and treated in order to reduce this risk, a small possibility that you could contract such an illness still remains. Ask your physician for further information.

This anemia medication is a category C FDA pregnancy drug. This means that taking this medicine during pregnancy could cause harm to the growing foetus. If you are pregnant or planning to become pregnant soon, you should not start a treatment with this medicine. It has not been determined whether Aranesp’s components can pass into breast milk. However, if you are currently nursing a child, you must not take this drug without your doctor’s approval. You should take all necessary precautions recommended by your doctor.

Aranesp is known to increase the risk of developing circulation or other life threatening disorders, including strokes and heart attacks. This risk is increased if you are following a long term treatment. If you experience any circulation or heart problems symptoms (such as a heavy feeling, chest pain, pain that spreads to the shoulder or to the arm, shortness of breath, slurred speech, imbalance or vision problems) you should seek immediate medical care.

Inform your physician if you feel light-headed, weak, pale or short of breath. This could be a sign that your body is no longer responding to your treatment with this anemia medication.

Aranesp Intake Guidelines

Ask your doctor how and when you should take this anemia medication in order to get the best results from your treatment. You must not ignore any of the instructions that your doctor has given you. If you fail to understand the instructions, consult a pharmacist, doctor or nurse. In order to prevent stomach upsets, this medicine should be taken with food or milk. Store this drug away from heat and moisture (preferably in the refrigerator). Do not allow the medicine to freeze.

Aranesp is administered as an injection. Do not shake the bottle/vial, as this could influence the consistency of the medication. Once the medication has been drawn into the syringe it should be administered immediately.

Aranesp Dosage

Your physician will determine the correct dose of this anemia medication that applies to you. You must not take extra doses of this drug without your doctor’s consent.

Aranesp Overdose

If you suspect that you could be suffering from an Aranesp overdose you should seek immediate medical attention. Contact your local poison control centre and alert your personal physician as soon as you can. In the case of an Aranesp overdose you might experience some of the following symptoms:

• Dizziness
• Headaches
• Itching
• Upper stomach fullness
• Facial redness
• Vision problems
• Shortness of breath

Aranesp Missed Dose

Aranesp Side Effects

You should stop your treatment with Aranesp and alert your physician as soon as possible if you experience any of these severe side effects:

• feeling short of breath;
• swelling of your feet and ankles;
• increased blood pressure (blurred vision, severe headache, chest pain, trouble concentrating, numbness, seizure);
• light-headedness, fainting;
• convulsions or black-out.

You may continue your treatment with Aranesp, but you should inform your physician, if you experience any of these lesser side effects:

• mild headache, dizziness;
• fever, body aches, sore throat, flu symptoms;
• muscle or joint pain;
• nausea, diarrhea, vomiting, constipation, stomach pain;
• bruising, warmth, swelling, bleeding, redness, oozing at the site of the injection.

Aranesp Drug Reactions

Ask your physician if you may take any other drugs during your treatment with Aranesp.

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