NEXAVAR

Nexavar Information

Nexavar is one of the most widely employed chemotherapeutic agents on the market. The use of this medical product affects the growth rate of the harmful cancer cells, thus slowing the spread of the disorder in the patient’s organism. Pharmacists characterize this product (Nexavar) as a multikinase inhibitor, which acts upon various kinases for threonine, serine and also for the tyrosine receptors, thus inducing the apoptosis of cells. The generic medical name of this remedy is Sorafenib.

Nexavar Indications

This anti-cancer medication is specifically prescribed in the therapy course of patients who are suffering from an advanced form of RCC (this abbreviation stands for renal cell carcinoma). In certain cases, individuals who suffer from kidney cancer may also be recommended to follow a treatment with Nexavar. You should rely on your physician’s expertise concerning other clinical cases in which the use of this chemotherapeutic agent may prove to be fruitful.

Nexavar Warnings

Before a patient can start a therapy course with Nexavar, he or she will have to discuss with their main medical specialist the advantages and risks that are associated with such a condition. It is important for all individuals to know that the use of this cancer drug can lead to the developing of hypertension. Thus, the administration of Nexavar must be applied in smaller doses, and must be constantly supervised in the case of patients who have a history of high blood pressure. Even those who have not suffered from this medical condition in the past may be asked to undergo regular blood pressure check-ups.

The presence of several other disorders may also encourage the patient’s medical specialist to seek an alternative cancer remedy that can be applied (with the same effectiveness as that of Nexavar) in the case of that specific patient. Thus, those who suffer from hemophilia or other blood clotting and / or bleeding disorders, medical history of heart attack and / or stroke, any other form of heart disease, and so on, may not be allowed to use Nexavar on a regular basis.

As this drug is a category D medication, its use is strictly forbidden in the case of pregnant females. The safety of use of this chemotherapeutic agent by nursing mothers is debatable, thus, such a therapy course should be avoided by a female who is nursing her infant.

Nexavar Intake Guidelines

It is important to employ all of your prescribed doses of Nexavar on an empty stomach. You should try to take the product 2 hours after one of your main meals or one hour before it. If you are not able to meet this requirement, you should at least try to take the medication along with a meal that is not rich in fat content. Patients who have stomach medical problems are generally unable to take their doses of Nexavar on an empty stomach, and as such they should discuss this matter with their PD who will determine an adequate dieting routine that will ensure that their therapy course with this medication is as effective as possible. Another issue that must be taken into consideration by a patient who is being treated with Nexavar is that the product’s tablets must not be crushed or chewed. They ought to be swallowed as a whole – taking the tablet along with water is known to ease the administration of the product.

Nexavar Dosage

Most adult patients are encouraged to employ 2 doses that consist in 400 mg of Nexavar per day, on a regular basis, however the dosage may change depending upon the individual’s clinical status, age, sex, and so on. For example, older adults and children, as well as patients who present a history of hypertension, may be prescribed lower doses of Nexavar. The only reliable source from which you can acquire the accurate amount of this chemotherapeutic agent that you are to employ on a regular basis is your personal health care provider.

Nexavar Overdose

All patients who are following a therapy course with Nexavar should be familiar with the symptoms that are commonly associated with over-dosage with this product, in order to be able to recognize this type of medical complication and to seek the appropriate clinical attention as quickly as possible. Some of the most common manifestations that have been accused by patients who had overdosed with Nexavar included: blistering, swelling, skin redness, rash, severe diarrhea, and so on.

Nexavar Missed Dose

Following a strict dosing routine with Nexavar is an important issue. In other words, missed doses of this chemotherapeutic agent must be dealt with and corrected (in a professional manner) as soon as possible. As doubling up doses of this medication is not recommended (it does not solve the problem and it increases your risk of experiencing overdose), we strongly recommend al patients who have missed one or more doses of Nexavar to refer to their PD and explain to him or her the situation. Follow your physician’s guidance.

Nexavar Side Effects

The use of Nexavar can lead to the developing of several side effects. The most severe clinical manifestations that can arise in case of a prolonged therapy course with this drug include: hypertension (and other associated symptoms), unusual bleeding, easy bruising, general illness, rapid weight gain, chest pain, convulsions, loss of coordination, headache, tiredness, and so on. If you experience any of these side effects, discontinue using Nexavar and seek emergency medical care.

Nexavar Drug Reactions

A therapy course with Nexavar should not be combined with the use of other medical products. The most common medicines that are known to harmfully interact with this cancer remedy include: blood thinners (Coumadin), Rifamate, Rimactane, Rifadin, Rifater, Decadron, Hexadrol, seizure drugs and other cancer drugs (Adriamycin, Rubex), etc. Seek further information from a medical professional.

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