KLIOGEST

Kliogest Information

Kliogest is a HRT medicine (hormone replacement therapy) that helps women who have passed their menopause and wish to stop having their periods. This drug acts by replacing the oestrogen and progesterone hormones, which your body stops producing after menopause.

Kliogest Indications

The menopause can bring such unpleasant symptoms as hot flushes, night sweats, insomnia, dry vagina, headaches, mood swings, lack of concentration or loss of energy, caused by the drop of hormone levels in your body. Also, the drop of estrogen levels causes greater loss of bone minerals causing the bones to become fragile and susceptible to breaking. With its oestrogen component, Kliogest helps relieve all these symptoms and the breaking of bones, while the progesterone component helps protect the lining of your womb from overstimulation with oestrogen. Kliogest may be prescribed for a number of other medical conditions. It is best that you consult with your personal health care specialist to find out exactly why you are prescribed treatment with this drug, and to obtain a list of directions specific to your case.

Kliogest Warnings

You should consult with your personal health care specialist before starting Kliogest treatment. There are some conditions that may require different dosage or special precautions, while others may entirely forbid treatment with Kliogest. Make sure your doctor knows your full medical history, and is able to give you a firm advice.
Conditions that may require special considerations before starting Kliogest treatment:

• Previous treatment with oestrogen-based products for menopausal symptoms – long term oestrogen treatment without a progesterone results in increased risk of cancer of the lining of the womb
• If you have had a Hysterectomy, your doctor may suggest a different medicine
• Less than one year has passed since your last natural period, as there may be other medicines better suited for this case.
• History of oestrogen-related circulatory problems, especially blood clots
• Liver disease
• History of epilepsy, migraine, diabetes, asthma, heart disease, high blood pressure may require constant monitoring during treatment.
• Endometriosis or fibroids of the womb. During Kliogest treatment, fibroids may increase in size and the symptoms of endometriosis may worsen.

The following are some of the conditions that may prevent you from taking Kliogest entirely:

• Being pregnant or having reasons to believe you are
• Confirmed or suspected hormone-dependant tumors, such as cancer of the breast or of the lining of the womb
• Porphyria (a rare blood pigment disease)
• Unusual and unexplained vaginal bleeding
• Allergies to any of the Kliogest ingredients
• Pains or swellings of the legs, or blood clots

Kliogest Intake Guidelines

It is advised that you set up a regular Kliogest intake schedule, so as to avoid missing any dose by accident. Take one tablet per day, accompanied by a glass of water, at around the same time of day, until all 28 tablets have been taken. Start the next pack the following day. If you are not following any other hormone-based treatment, you can start on Kliogest in any convenient day. Otherwise, it is recommended that you start your treatment in the last day of your period-like bleed. Consult with your personal health care specialist to determine when is the best time for you to start your Kliogest treatment.

Kliogest Dosage

Talk to your personal health care specialist to obtain the Kliogest dosage best suited for you. Follow the prescribed dosage without altering it in any way, either by modifying the intake schedule or the dosage itself.

Kliogest Overdose

The known symptoms of Kliogest overdose are nausea and vomiting, but the long-term implications may be more severe. If you have reasons to suspect you are suffering from an overdose with this drug, immediately contact your personal health care specialist to determine the appropriate course of action to be taken.

Kliogest Missed Dose

If you happen to miss a dose of Kliogest, take it as soon as you remember and continue with your regular schedule. If it is almost time for the next intake, throw the tablet away and carry on with the regular schedule, but let your personal health care specialist know about this in case any other actions need to be taken. Missing any Kliogest doses may cause vaginal bleeding or spotting.

Kliogest Side Effects

There may appear signs of irregular bleeding or spotting – that is a normal effect and it may take several months until you become period-free. You should however contact your doctor if the spotting or bleeding suddenly becomes heavier, or if any of the effects become too bothersome. Some side effects can be particularly bothersome, and may require interruption of the treatment:

• severe pain or swelling of the legs
• yellowing of the skin or eyes (jaundice)
  migraines, or sudden severe headache
• eyesight problems
• marked rise in blood pressure
• vaginal bleeding or spotting after some time of being period-free
• known or suspected pregnancy

There have been recorded cases of cancer of the breast, liver problems and blood clots associated with Kliogest therapy. However, these are particular cases and should not weigh too heavily in your choice of starting your treatment.

Kliogest Drug Reactions

Tell your personal health care specialist about any other medicines you are taking or planning to take in the future, as some of them may interfere with Kliogest action in the body. Most importantly, ensure that your physician knows about any other oestrogen medicines and medicines for tuberculosis, epilepsy, depression or sleeping disorder you are currently taking, or will be taking in the future.

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