TRENTAL (PENTOXIFYLLINE)

Trental Information

Trental is a drug also generically known under the name of Pentoxifylline. Trental is meant to make some changes regarding the shape of your body’s red blood cells. Therefore, Trental enables your body’s red blood cells to properly fit into the smaller arteries (the smallest blood vessels).

Trental (Pentoxifylline) is successfully used in the treatment of patients that need to improve their blood flow. An improved blood flow usually helps reduce bothersome conditions such as leg cramps or any other vascular disorder symptoms (this is a disease that has been related to the body’s arteries and veins).

Trental Indications

Trental Warnings

You may not be allowed to start taking Trental (Pentoxifylline) if you have recently suffered from brain or eye hemorrhaged (bled), or if you are suffering from allergies to this drug or to any of its components - theophylline (Theo-Bid, Theo-Dur), to caffeine, or theobromine.

It is highly recommended that you should inform your doctor before you start taking this drug if you are suffering from any of the following medical conditions:

• ulcer disease (duodenal or stomach ulcer);
• have had any type of surgery in the last couple of weeks (this also includes dental surgeries);
• have recently suffered or experienced any type of bleeding disorders;
• liver disease.

If you are suffering from any of the medical conditions that have been listed here, you may not be allowed to take Trental, or you might have to take a lower dose of this drug. Also, you personal physician might want to monitor the way in which your body responds to your treatment with Trental.

Trental is a Category C FDA pregnancy drug. Therefore, it has not been clearly determined the effects that a treatment with Trental has on an unborn child (it is not known if it can cause harm to the fetus or to the carrying mother). It is highly recommended that you should consult with your personal physician before you start taking this drug if you are pregnant or if you are planning to be so soon. It is known that Trental can and does pass into breast milk. Therefore, taking this drug while you are nursing an infant might harm the baby. Consult with your doctor before you start a treatment with this drug if you are breastfeeding your child.  

Trental Intake Guidelines

Trental pills must not be chewed, broken or crushed. You must try to swallow them in one piece, because they have been designed (with a special “coat”) so they cannot have harmful effects on your stomach. You must not stop your treatment with Trental without your personal physician’s approval even if you start to feel better. Avoid smoking during your treatment with this drug, because tobacco is known to decrease the drug’s beneficial effects (it narrows the body’s blood vessels). If you have a smoking habit, you should ask your doctor for further advice.

You must take this drug according to your doctor’s instructions. If you fail to understand some of them, you should ask a pharmacist, a doctor or a nurse. You should accompany each dose of Trental with a glass of water (8 ounces of liquid). It is recommended to take this drug on a full stomach in order to avoid stomach upset. Trental should be kept out of the children’s reach, away from heat, moisture and direct sunlight,

Trental Dosage

Trental Overdose

If you suspect that you are suffering from overdose with this drug, you are in need of medical care. Overdose symptoms are seizures, fever, agitation, flushed face, loss of consciousness, and drowsiness.

Trental Missed Dose

If you miss one of your Trental doses, take the pill as soon as you remember. If more than 3 hours have passed since your regular dosing time you should skip the pill that you have missed and then continue with your dosing schedule.

Trental Side Effects

Trental Drug Reactions

Before taking Trental, you must inform your doctor if you are taking any other drugs, especially if they are warfarin (Coumadin), theophylline (Theo-Bid, Theo-Dur, Theocron, Theolair, Slo-Phyllin, Elixophyllin, etc), aminophylline (Truphylline, Phyllocontin), dyphylline (Dylix, Dilor, Lufyllin, Neothylline), or oxtriphylline (Choledyl).
There are other drugs that have not been listed here, but they can (and sometimes do) interact with Trental. Therefore, it is highly recommended that you ask for your doctor’s consent before taking any other drugs, even if they are over-the-counter drugs like vitamins, minerals, herbal products, cold or cough medicines, etc.

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