Zenapax (DACLIZUMAB)

Zenapax Information

Brand name for daclizumab, Zenapax belongs to the immunosuppressant monoclonal antibody category of drugs. An immunosuppressant, Zenapax helps in stopping the body from rejecting a kidney after transplantation. Always used with other drugs, Zenapax limits the functions of the immune system of a body. Mostly, Zenapax works as an immunosuppressive agents in patients who have just undergone kidney transplantation. After an individual is given a substitution of his own kidney, through transplantation, the white blood cells or W.B.C protests the most against it. The whole immune system tries utmost to outwit the transplanted kidney. This is where an immunosuppressant like Zenapax plays a crucial role. Zenapax fights against the W.B.C to stop them from rejecting the transplanted kidney. Consequently the whole immune system falls inactive, hampering the body’s ability to combat infections. Zenapax, already a popular name, may be used for various other diseases by doctors.

Zenapax Warnings

Before taking in Zenapax, it needs to be borne clearly in mind that use of Zenapax may lead to higher risks of developing certain specific types of cancer like lymphoma. Don’t take in grapes or grape juice while you are on medication as it can enhance the chances of having more and more side effects. Always inform your doctor before hand if you had any kind of allergy to Zenapax in the past. Your physician may also need to know if you are suffering from any active or chronic viral, bacterial, or fungal infection. Tell the doctor if you are already taking drugs belonging to the immunosuppressant category. Don’t use Zenapax if you are already suffering from Cancer and blood sugar. The use of this drug with such diseases may aggravate the situation.

Listed in the FDA pregnancy category C, Zenapax crosses the placenta. But there is still no definite evidence of its having harmful effects on an embryo. But pregnant women should take precautions if they need to take this drug during pregnancy. Doctors are still into the dark as to whether this drug passes into breast milk or not. Your doctor is the best person to consult with regarding this, if you have a nursing baby. However, it has been proven that Zenapax may cause high blood pressure and dehydration amongst children.

Consult your doctor before taking any kind of vaccination during the treatment of Zenapax. There are chances of adverse reactions in such cases. Also don’t get close to people who have taken "live" vaccines like oral polio vaccine, nasal influenza vaccine very recently, as there is a chance of the virus getting transmitted on to you.

Zenapax Side Effects

Although used and valued as a beneficial drug, Zenapax can have lots of side effects. The serious side effects of Zenapax include breathing trouble, blocked throat, swollen lips, tongue, or face. Consult a doctor immediately if you experience any one of these. Amongst the most common side effects of Zenapax, stomach upset, vomiting, diarrhea or constipation, drowsiness, headache, swollen hands, feet or legs are notable.

Side effects like chest pain, cough, fever, fast heart beat, reddish skin at incision, short breath, fatigue are also common. Users may also suffer from sleep disorders, heartburn, slow healing of wound and frequent urination. Don’t ignore if any of these side effects appear.

Zenapax Overdose

It is always the best to take the right dose on right time for the best results. Although no severe cases of Zenapax overdose have been reported so far, but it is apprehended that severe consequences may await patients taking in double dose. No symptoms of Zenapax overdose are known. Rush to a doctor immediately after you realize that you have taken in overdose.

On the other hand, missed dose of Zenapax may not be fatal. Take in the dose as soon as you remember that you have missed a dose. But if it is already time for the next scheduled dose, go for the scheduled one leaving the missed one.

Zenapax Usage Guidelines

Your attending physician is the best person to provide you with usage guidelines. Normally the first dose of daclizumab is given within 24 hours of the kidney transplant. Additional doses are given at 14-day intervals depending upon health conditions. Special care needs to be taken while mixing the suspension for injection. Remember no to shake the mixture. Use the solution within 4 hours of mixing. Store the medicine as asked by the pharmacists. Also don’t ignore taking up any diagnostic tests, which your doctor may want you to take up during medication. Also try and maintain dental hygiene and visit a dentist regularly. Women should not forget to use result oriented contraceptive measures during medication.

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