Beta is an active topical corticosteroid which produces a rapid response in those inflammatory dermatoses that are normally responsive to topical corticosteroid therapy, and is often effective in the less responsive conditions such as psoriasis. Beta preparations are indicated for the treatment of: eczema, including atopic, infantile and discoid eczemas, prurigo nodularis; psoriasis (excluding widespread plaque psoriasis); neurodermatoses, including lichen simplex, lichen planus; seborrhoeic dermatitis; contact sensitivity reactions; discoid lupus erythematosus; insect bite reactions; prickly heat; and they may be used as an adjunct to systemic steroid therapy in generalised erythroderma.
Beta Cream Warnings
Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur even without occlusion. Systemic absorption resulting in adrenal suppression may occur especially under occlusion with weekly doses of over 30g. Routine steroid precautions must be observed if the patient is stressed. Infants and children up to four years should not be treated with topical steroids for longer than 3 weeks without medical review. In infants, the napkin may act as an occlusive dressing, and increase absorption. The face, more than other areas of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. Application to the face is therefore undesirable except for very brief periods and except when treating such conditions as psoriasis, discoid lupus erythematosus and severe eczema. If applied near the eyes, care is needed to ensure that the preparation does not enter the eye, as glaucoma or cataract might result. Co-existing infection may require specific chemotherapy or withdrawal of topical corticosteroid therapy. Bacterial infection is encouraged by the warm, moist conditions induced by occlusive dressings, and so the skin should be cleansed before a fresh dressing is applied. Prolonged use on the flexures and intertriginous areas is undesirable. Topical steroids may be hazardous in psoriasis for a number of reasons, including rebound relapses, development of tolerance, risk of generalized pustular psoriasis and development of local or systemic toxicity due to impaired barrier function of the skin. If used in psoriasis careful patient supervision is important. Use in Pregnancy and Lactation: Topical administration of corticosteroids to pregnant women has not been established; however, topical steroids should not be used extensively in pregnancy, i.e. in large amounts or for prolonged periods. The use of fluorinated steroids is contraindicated on the face.
Beta Cream Side Effects
Prolonged and intensive treatment with highly active corticosteroid preparations may cause local atrophic changes in the skin such as striae, thinning and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or when skin folds are involved. Prolonged use of large amounts can result in sufficient systemic absorption to produce the features of hypercorticism. There are reports of pigmentation changes and hypertrichosis with topical steroids.
Beta Cream Overdose
Acute over dosage is unlikely to occur, however, in the case of chronic over dosage or misuse, the features of hypercorticism may appear and in this situation topical steroids should be discontinued.
Beta Cream Usage guidelines
A small quantity of Beta should be applied to the affected area two or three times daily until improvement occurs. It may then be possible to maintain improvement by applying once a day, or even less often. BETA Cream is especially appropriate for moist or weeping surfaces. In the more resistant lesions, such as the thickened plaques of psoriasis on the elbows and knees, the effect of BETA can be enhanced, if necessary, by occluding the treatment area with polythene film. Store below 25°C.
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