RAPAMUNE

Rapamune Information

Rapamune is a popular medicine that is more commonly known under the name of Sirolimus. This medicine is known to effectively lower the organism’s immune system, the one that helps the patient’s organism fight infections. However, the patient’s immune system is the one that “rejects” a transplanted organ (for example a kidney or a liver).

Rapamune Indications

Rapamune Warnings

Before you start taking this medicine (Rapamune) you should inform your personal physician if you are suffering from known allergies to any medicines, foods, dyes or preservatives or if you have:

• high triglycerides or cholesterol;
• liver disease;
• cytomegalovirus (CMV);
• kidney disease.

Patients who have the medical conditions that have been listed here might not be allowed to start taking this medicine or might be prescribed a lower dose of Rapamune.

Rapamune Intake Guidelines

Ask your personal doctor how to use Rapamune. You ought to avoid disobeying any of your personal physician’s instructions. If you fail to understand some of them, you should ask a nurse or a pharmacist to properly explain them to you. We also recommend you to carefully read the instructions from the medicine’s label for further information about this medical product.

A tablet of Rapamune (a dose of this medicine) ought to be accompanied by a full glass of liquid. Ask your physician how to use the liquid form of this drug. You ought to use a special measuring device (such as a measuring cup, or a measuring spoon) in order to effectively measure your correct dose of this drug (Rapamune). If you do not own such a device, buy one from your local pharmacy.

Because this product is not known to cause stomach upset, it may be taken in either on an empty or on a full stomach. During your treatment with this medicine (Rapamune) your personal health care provider might ask you to undergo regular medical tests. Store Rapamune in a place that is away from heat and moisture and which cannot be easily reached by pets and children.

Rapamune Dosage

Rapamune Overdose

If you suspect that you might be suffering from an overdose with Rapamune you should seek emergency medical attention. We have no information about the possible symptoms that could be triggered by such a medical condition. Ask your personal physician for more information and / or advice.

Rapamune Missed Dose

If you miss taking one of your scheduled doses of Rapamune, we strongly recommend you to take it as soon as you can. If it is time for another prescribed dose, skip the one that you have missed and proceed with your regular dosing schedule. Do not double dose without your personal physician’s approval.

Rapamune Side Effects

Patients who are following a treatment with Rapamune and who develop any of these dangerous symptoms should immediately stop using this medicine and seek emergency medical attention:

• fast heart rate;
• body aches, fever, chills, flu symptoms;
• pale skin, easy bleeding or  bruising, weakness;
• cough, breathing problems, chest tightness;
• burning or pain when you urinate.

You need not stop using this medicine, but your should nevertheless alert your personal physician if you develop any of these less severe but more common side effects of Rapamune:

• joint pain;
• headache;
• vomiting, nausea, constipation, diarrhea, stomach pain;
• tremors;
• weight gain, swelling of your feet or hands;
• skin rash or acne.

Rapamune Drug Reactions

Patients who are currently following a treatment with Rapamune should alert their personal health care specialist if they want to start using any of these medical products:

• amphotericin B (AmBisome, Fungizone, Amphotec, Abelcet);
• cimetidine (Tagamet);
• bromocriptine (Parlodel);
• cisapride (Propulsid);
• metoclopramide (Reglan);
• danazol (Danocrine);
• rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rimactane), rifapentin (Priftin);
• tacrolimus (Prograf);
• St. John's wort;
• ACE inhibitors like fosinopril (Monopril), captopril (Capoten), benazepril (Lotensin), lisinopril (Prinivil, Zestril), enalapril (Vasotec), perindopril (Aceon), moexipril (Univasc), ramipril (Altace), quinapril (Accupril), or trandolapril (Mavik);
• Antibiotics like fluconazole (Diflucan), clotrimazole (Mycelex Troche), ketoconazole (Nizoral), itraconazole (Sporanox), clarithromycin (Biaxin), voriconazole (Vfend), erythromycin (E-Mycin, Erythrocin, Ery-Tab, E.E.S), capreomycin (Capastat), telithromycin (Ketek), or vancomycin (Vancoled, Vancocin);
• antiviral drugs like cidofovir (Vistide), adefovir (Hepsera), acyclovir (Zovirax), or foscarnet (Foscavir);
• calcium channel blockers like nicardipine (Cardene), diltiazem (Cardizem, Tiazac), or verapamil (Covera, Calan, Verelan);
• cancer drugs like aldesleukin (Proleukin), streptozocin (Zanosar), carmustine (Gliadel, BiCNU), ifosfamide (Ifex), cisplatin (Platinol), plicamycin (Mithracin), oxaliplatin (Eloxatin), or tretinoin (Vesanoid);
• HIV drugs like atazanavir (Reyataz), indinavir (Crixivan), amprenavir (Agenerase), saquinavir (Invirase), ritonavir (Norvir), lopinavir/ritonavir (Kaletra), or nelfinavir (Viracept); or
• drugs that are supposed to treat seizures, like phenytoin (Dilantin), carbamazepine (Tegretol), phenobarbital (Luminal).

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